Synthesis of new chalcone derivatives bearing 2,4-thiazolidinedione and benzoic acid moieties as potential anti-bacterial agents

Liu, Xiaofang; Zheng, Chang‐Ji; Sun, Liang‐Peng; Liu, Xue‐Kun; Piao, Hu‐Ri

doi:10.1016/j.ejmech.2011.05.012

Cited by 104 publications

(29 citation statements)

References 7 publications

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“…Liu et al 16 Synthesized a series of chalcone derivatives bearing the 2,4-thiazolidinedione and benzoic acid moieties evaluated for their antibacterial activity. In tested compounds, the most effective results obtained with MIC value in the range of 0.5-4mg/mL against six Gram-positive bacteria.…”

Section: As Anti-inflammatory Agentmentioning

confidence: 99%

Thiazolidinedione Derivatives as Antidiabetic Agents: A Short Review

Geetha¹,

Gunasekaran²,

Reddy³

2018

Int. Res. J. Pharm.

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In the present scenario, researchers focused themselves on thiazolidine ring-based compound to cure Diabetes Mellitus. Diabetes mellitus is a heterogeneous group of disease, characterized by a state of chronic hyperglycemia, resulting from diversity of etiologies, environmental and genetic, acting jointly. The thiazolidinediones used in oral combination therapy in management of patients with type II diabetes who have insufficient glycemic control despite maximal tolerated dose of oral mono-therapy with either metformin or sulphonyl urea.

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Section: As Anti-inflammatory Agentmentioning

confidence: 99%

Thiazolidinedione Derivatives as Antidiabetic Agents: A Short Review

Geetha¹,

Gunasekaran²,

Reddy³

2018

Int. Res. J. Pharm.

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“…From the big family of heterocyclic compounds, 1,3-thiazolidine-2,4-diones show a wide spectrum of chemo -therapeutic properties and a considerable amount of work has been done on the synthesis of thiazolidinedione derivatives as potent antibacterial and antifungal agents (Gouveia et al, 2009, Liu et al, 2011. Chromone and related compounds are wide-spread in nature and exhibit a wide range of pharmacological activity like antibacterial, antifungal (Hatzade et al, 2010, Ali andIbrahim, 2010), antitumor, anti-oxidant, anti-HIV, antiulcerant, anti-inflammatory.…”

Section: Sirmentioning

confidence: 99%

Antimicrobial screening of new 5-(chromene-3-yl)methylene-2,4-thiazolidinediones

Nastasă

Duma

Tiperciuc

et al. 2015

Bangladesh J Pharmacol

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“…Correspondingly, chalcones bearing 2,4-thiazolidinedione and benzoic acid moieties (VIII) presented potential anti-bacterial activity against gram positive bacteria, particularly against multidrug-resistant strains of clinical isolates [28]. Moreover, integration of 5-nitroisoquinolines (IX) and Abacavir prodrugs (X) with Schiff bases enhanced the anti-malarial and anti-HIV scope of these compounds [29,30].…”

Section: Introductionmentioning

confidence: 99%