Synthesis of new oxindole derivatives containing oxazolidin-2-one

Abstract

The reactions of bis(2-chloroethyl)amine in presence of potassium carbonate with substituted isatins afforded the corresponding 1-[2-(2-oxo-1,3-oxazolidin-3-yl)ethyl)indoline-2,3-diones, which are used as starting materials for the preparation of new heterocyclic systems containing quinoxaline, oxazolidine, benzimidazoquinazoline and oxindole nuclei. The structures of the products were established by NMR spectroscopy, mass spectra and X-ray diffraction analysis.