Synthesis Of New P-substituted Iminophosphoranes Via Staudinger Raction And Antimicrobial Activity Evaluation

Golla, Madhava; Subramanyam, Ch.; Basha, Sk. Thaslim; Babu, P. Jawahar; Raju, C. Naga

doi:10.1080/10426507.2015.1064919

Cited by 1 publication

(1 citation statement)

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“…Phosphorus/nitrogen‐containing compounds have been widely studied because of their interesting chemistry, with special attention in pentavalent‐phosphorus derivatives such as the well‐known iminophosphoranes or phosphazenes [1–3], which have been considered versatile compounds in the field of synthetic organic chemistry with wide applications as precursors [4], organocatalysts [5], and final products with interesting bioactivities [6].…”

Section: Introductionmentioning

confidence: 99%

Reactivity of pyrimidinylphosphazenes with acetylenic esters: Competitive [4 + 2] and [2 + 2] tandem cycloaddition or retro‐cycloaddition approaches

Cobo

Molina

Sánchez

et al. 2022

Journal of Heterocyclic Chem

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In the search for new intermediates for heterocyclic synthesis, the reactivity of 6‐iminophosphoranepyrimidines against dimethyl acetylenedicarboxylate (DMAD) and ethyl propiolate as dienophiles, was studied in this work. The presence of a viable 2‐azadienic moiety in pyrimidin‐4‐one rings (oxo derivatives) favored reaction of DMAD by [4 + 2]/retro‐[4 + 2] sequence, in addition to the expected [2 + 2] cycloaddition/retrocycloaddition involving phosphazene moiety. In contrast, pyrimidine derivatives lacking a viable 2‐azadienic residue reacted only through phosphazene group by the aforementioned [2 + 2]/retro‐[2 + 2] tandem process. Ethyl propiolate (non‐symmetric dienophile) proved less reactive in the study, giving rise to undesired side reactions.

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Section: Introductionmentioning

confidence: 99%