Synthesis of New Pyrazoles via Cycloaddition Reactions of Nitrilimines with 2‐Cyclopentenone Derivatives

Dependence of Electrical Properties on Frequency and Temperature for Novel Cyclopentenone Derivatives

“…The cyclopentenone derivatives (samples 1-3) were prepared by the interaction of 3, 4 -Diphenyl-4-hydroxy-2cyclopentenone (sample1) with hydrazonyl chlorides and triethylamine and characterized by FTIR spectroscopy, NMR and mass spectra according to our previously work [15] . Fig.…”

“…The values of the entropy changes of dielectric relaxation ΔS were -59 and -77. 15. The values of entropy are negative indicating that the relaxation process is the rate determining factor.…”

“…3, 4-Diphenyl-4-hydroxy-2-cyclopentenone (sample 1) was synthesized as previously described in the literature [14] . While the synthesis of 1,3,6,6a-tetraphenyl-1,6a-dihydrocyclopenta[c]pyrazol-4(3aH) one (sample 2) and 1-(3-Chlorophenyl)-3,6,6a-triphenyl-1,6a-dihydrocyclopenta[c]pyrazol-4(3aH)-one (sample 3) were synthesized using literature [15] . To a mixture of sample 1 (5 m mole), hydrazones chlorides (5 mmole) and triethylamine (1.5 mL) in dry benzene was heated under reflux.…”

Diastereodivergent Synthesis of Pyrazoline Derivatives through [3 + 2] Cycloaddition of Baylis–Hillman Adducts and Nitrilimines

“…Remogliflozin Etabonate VI is effective in the treatment of nonalcoholic steatohepatitis, type 2 diabetes, and obesity . The varied bioactivities of pyrazolines have encouraged synthetic chemists to develop efficient methods, especially cycloaddition reactions, to access these compounds and their derivatives .…”

Regioselective Synthesis of Mono‐ and Dispiropyrazoline Derivatives via 1,3‐dipolar Cycloaddition with Nitrilimines

“…In the continuation of our work on 1,3‐dipolar cycloaddition reactions , we therefore investigated the possibility to construct this targeted scaffold via 1,3‐dipolar cycloaddition using ( E , E )‐1,3‐bis(arylidene)indan‐2‐ones across diarylnitrilimines. Note that the use of diarylnitrilimines in cycloaddition across alkenes and other dipolarophiles allowing the construction of N ‐heterocyclic systems is well documented in the literature .…”