2016
DOI: 10.1134/s1070428016010139
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Synthesis of new sulfonamide derivatives of thiazolo[3,2-a]quinazolin-5-one

Abstract: A general procedure has been proposed for the synthesis of thiazolo[3,2-a]quinazolin-5-one derivatives containing a sulfonamide group on C 7 via intramolecular nucleophilic substitution of halogen in 2-halo-5-sulfamoyl-N-(1,3-thiazol-2-yl)benzamides. The effects of the degree of activation of the initial compound and halogen nature on the yield of the target products have been analyzed.

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