Synthesis of nickel nanoparticles by chemical and green route and their comparison in respect to biological effect and toxicity

Sudhasree, S.; Banu, Afreen; Brindha, P.; Kurian, Gino A.

doi:10.1080/02772248.2014.923148

Cited by 176 publications

(75 citation statements)

References 17 publications

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“…The average hydrodynamic particle diameter in water shows particle aggregation. Our characterizations results are consistent with Sudhasree et al for aggregation of NPs in aqueous medium. Furthermore, elemental composition of NiONPs was studied using EDS, which shows the presence of both Ni and O in the sample.…”

Section: Resultssupporting

confidence: 93%

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Green synthesis and characterizations of Nickel oxide nanoparticles using leaf extract of Rhamnus virgata and their potential biological applications

Iqbal

Abbasi

Mahmood

et al. 2019

Applied Organom Chemis

145

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In the present report, Nickel oxide nanoparticles (NiONPs) were synthesized using Rhamnus virgata (Roxb.) (Family: Rhamnaceae) as a potential stabilizing, reducing and chelating agent. The formation, morphology, structure and other physicochemical properties of resulting NiONPs were characterized by Ultra violet spectroscopy, X-ray diffraction (XRD), Fourier Transform Infrared analysis (FTIR), Scanning electron microscopy (SEM), Energy-dispersivespectroscopy (EDS), Transmission electron microscopy (TEM), Raman spectroscopy and dynamic light scattering (DLS). Detailed in vitro biological activities revealed significant therapeutic potential for NiONPs. The antimicrobial efficacy of biogenic NiONPs was demonstrated against five different gram positive and gram negative bacterial strains. Klebsiella pneumoniae and Pseudomonas aeruginosa (MIC: 125 μg/mL) were found to be the least susceptible and Bacillus subtilis (MIC: 31.25 μg/mL) was found to be the most susceptible strain to NiONPs. Biogenic NiONPs were reported to be highly potent against HepG2 cells (IC 50 : 29.68 μg/ml). Moderate antileishmanial activity against Leishmania tropica (KMH 23 ) promastigotes (IC 50 : 10.62 μg/ml) and amastigotes (IC 50 : 27.58 μg/ml) cultures are reported. The cytotoxic activity was studied using brine shrimps and their IC 50 value was recorded as 43.73 μg/ml. For toxicological assessment, NiONPs were found compatible towards human RBCs (IC 50 : > 200 μg/ml) and macrophages (IC 50 : > 200 μg/ml), deeming particles safe for various applications in nanomedicines. Moderate antioxidant activities: total antioxidant capacity (TAC) (51.43%), 2,2-diphenyl-1-picrylhydrazyl (DPPH) activity (70.36%) and total reducing power (TRP) (45%) are reported for NiONPs. In addition, protein kinase and alpha amylase inhibition assays were also performed. Our results concluded that Rhamnus virgata synthesized NiONPs could find important biomedical applications with low cytotoxicity to normal cells.

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Section: Resultssupporting

confidence: 93%

“…NiONPs also have applications in the adsorption of toxic environmental pollutants and dyes . Because of their anti‐inflammatory property, NiONPs can also be used in biomedicines . The previous research work of NiONPs have revealed cytotoxic effects by releasing ROS and Ni ++ to oxidative damage …”

Section: Introductionmentioning

confidence: 99%

Green synthesis and characterizations of Nickel oxide nanoparticles using leaf extract of Rhamnus virgata and their potential biological applications

Iqbal

Abbasi

Mahmood

et al. 2019

Applied Organom Chemis

145

View full text Add to dashboard Cite

show abstract

“…For example, nickel NPs made from root extracts were nontoxic to mammalian cells compared with the same ones made using conventional chemistry. 49 During the past years, as mentioned earlier, different methodologies have been studied to produce NPs. For instance, Liu et al prepared tellurium (Te) nanotubes with a controllable size and morphology by using a microwave approach and monosaccharides as reducing agents.…”

Section: Introductionmentioning

confidence: 99%

<p>Comparison of cytocompatibility and anticancer properties of traditional and green chemistry-synthesized tellurium nanowires</p>

Vernet-Crua¹,

David²,

Zhang³

et al. 2019

IJN

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Background: Traditional physicochemical approaches for the synthesis of compounds, drugs, and nanostructures developed as potential solutions for antimicrobial resistance or against cancer treatment are, for the most part, facile and straightforward. Nevertheless, these approaches have several limitations, such as the use of toxic chemicals and production of toxic by-products with limited biocompatibility. Therefore, new methods are needed to address these limitations, and green chemistry offers a suitable and novel answer, with the safe and environmentally friendly design, manufacturing, and use of minimally toxic chemicals. Green chemistry approaches are especially useful for the generation of metallic nanoparticles or nanometric structures that can effectively and efficiently address health care concerns. Objective: Here, tellurium (Te) nanowires were synthesized using a novel green chemistry approach, and their structures and cytocompatibility were evaluated. Method: An easy and straightforward hydrothermal method was employed, and the Te nanowires were characterized using transmission electron microscopy, scanning electron microscopy, energy-dispersive X-ray spectroscopy, Fourier-transform infrared spectroscopy, X-ray powder diffraction, X-ray photoelectron spectroscopy, and optical microscopy for morphology, size, and chemistry. Cytotoxicity tests were performed with human dermal fibroblasts and human melanoma cells (to assess anticancer properties). The results showed that a treatment with Te nanowires at concentrations between 5 and 100 μg/mL improved the proliferation of healthy cells and decreased cancerous cell growth over a 5-day period. Most importantly, the green chemistry-synthesized Te nanowires outperformed those produced by traditional synthetic chemical methods. Conclusion: This study suggests that green chemistry approaches for producing Te nanostructures may not only reduce adverse environmental effects resulting from traditional synthetic chemistry methods, but also be more effective in numerous health care applications.

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“…Tetrahedral and octahedral complexes of spinel ferrite structure show vibrating absorption bands at 596 cm ‐1 and 418 cm ‐1 , respectively . The peak at 1402.27 cm ‐1 in the spectrum of NiFe 2 O 4 ‐MWCNTs is related to stretching vibration absorption band of Ni‐O bond in nickel‐doped nanocrystal …”

Section: Resultsmentioning

confidence: 98%

Nanocomposite based on epoxy and MWCNTs modified with NiFe₂O₄ nanoparticles as efficient microwave absorbing material

Hosseini

Mahdavi

2018

Applied Organom Chemis

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In order to make a microwave absorbent material with good dielectric and magnetic properties, well dispersed microwave absorbing hybrid epoxy polymer composites containing nickel doped Fe 3 O 4 nanocrystals coated on carbon nanotubes (NiFe 2 O 4 -MWCNTs/epoxy) were synthesized by the combined precipitation-hydrothermal method in 1-30 wt.% of nanoparticles. Nickel possess well interaction with microwave radiation and represents fine electromagnetic interference (EMI) shielding and by dopping it into ferrite spinel structures, does not show any tendency to oxidation. Well-dispersed NiFe 2 O 4 -MWCNTs/epoxy nanocomposite prepared by new in-situ polymerization method. First, NiFe 2 O 4 -MWCNT nanoparticles ultrasonicated in acetone and after mixing with epoxy resin ultrasonicated again. Finally, hardner added to the composite and tuned temperature for evaporating solvent. X-ray diffraction (XRD) and energy dispersive spectroscopy (EDS) confirmed the synthesizing NiFe 2 O 4 nanoparticles. Saturation magnetization value of NiFe 2 O 4 -MWCNTs is about 29 emu/g with very low remanence and coercivity content, which revealed that the NiFe 2 O 4 -MWCNTs is ferromagnetic nanocrystal. Transmission electron microscopy (TEM) used to characterize the distribution of NiFe 2 O 4 nanocrystals on the surface of MWCNTs. The TEM images show that NiFe 2 O 4 nanocrystals have a mean size of 12 nm, and completely coated on the exterior surface of MWCNTs. The obtained results of reflection loss revealed that the maximum values of reflection loss of the NiFe 2 O 4 -MWCNTs/epoxy increase by enhancing the content of nanoparticles until 10 wt.% and decreases in 30 wt.%.

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Synthesis of nickel nanoparticles by chemical and green route and their comparison in respect to biological effect and toxicity

Cited by 176 publications

References 17 publications

Green synthesis and characterizations of Nickel oxide nanoparticles using leaf extract of Rhamnus virgata and their potential biological applications

Green synthesis and characterizations of Nickel oxide nanoparticles using leaf extract of Rhamnus virgata and their potential biological applications

<p>Comparison of cytocompatibility and anticancer properties of traditional and green chemistry-synthesized tellurium nanowires</p>

Nanocomposite based on epoxy and MWCNTs modified with NiFe₂O₄ nanoparticles as efficient microwave absorbing material

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Synthesis of nickel nanoparticles by chemical and green route and their comparison in respect to biological effect and toxicity

Cited by 176 publications

References 17 publications

Green synthesis and characterizations of Nickel oxide nanoparticles using leaf extract of Rhamnus virgata and their potential biological applications

Green synthesis and characterizations of Nickel oxide nanoparticles using leaf extract of Rhamnus virgata and their potential biological applications

<p>Comparison of cytocompatibility and anticancer properties of traditional and green chemistry-synthesized tellurium nanowires</p>

Nanocomposite based on epoxy and MWCNTs modified with NiFe2O4 nanoparticles as efficient microwave absorbing material

Contact Info

Product

Resources

About

Nanocomposite based on epoxy and MWCNTs modified with NiFe₂O₄ nanoparticles as efficient microwave absorbing material