Synthesis of novel acylthioureas bearing naphthoquinone moiety as dual sensor for high-performance naked-eye colorimetric and fluorescence detection of CN− and F− ions and its application in water and food samples

Anti‐inflammatory Potential of 1,4‐Naphthoquinone Acyl Thiourea Hybrids on Lipopolysaccharide‐Activated Mammalian Macrophages, and Their Acid Dissociation Constants

“…New and known 1,4‐naphthoquinone acyl thiourea hybrids 1 – 7 were synthesized by reaction of the 2,3‐diaminonaphthalene‐1,4‐dione, which was prepared according to a literature method, [37] and corresponding acyl isothiocyanates which were synthesized by reacting various acyl chlorides with potassium thiocyanate in acetone under reflux temperature for 1 h (Scheme 1). The 2,3‐diaminonaphthalene‐1,4‐dione dissolved in acetone was added dropwise to the reaction flask of the isothiocyanate compounds obtained after 1 h reaction in acetone, and the desired products 1 – 7 were obtained after 12 h. The molecular structure of the pure new product 2 was characterized by 1 H NMR, 13 C NMR, FT‐IR, HRMS, and elemental analysis, and molecular structures of the pure known products 1 , 3 – 7 were confirmed using 1 H NMR, melting point, which were in agreement with the data in reference, [37] and elemental analysis (See SI part).…”

A Novel Fluorescent Probe for the Detection of Cyanide Ions in Solutions and Studies on Its Biophysical Interactions with ctDNA and Proteases

“…Finally, to investigate the sensor properties, the behavior of Ci towards the aqueous solution of bitter almond was examined. For this, the sample of 30 g of crushed bitter almond was placed in flask containg 0.5 g of NaOH and 100 mL of water, after stirring for 20 min final mixture solution was filtered [25]. After the addition of 20 µL of bitter almond, the maximum absorption peak of Ci showed a significant blue shift accompanied by a decrease in absorbance.…”

Spectrophotometric Fluoride Determination Using St. John’s Wort Extract as a Green Chromogenic Complexant for Al(III)

“…Spectrophotometry is a versatile and good alternative technique for determining the concentration of inorganic ions in water samples, having many advantages such as low cost, ease of applicability, fast analysis, reliability, high sensitivity at low concentrations, and wide analytical working range . In spectrophotometric methods, dyestuff-metal complexes, − nanoparticles, , or synthesized organic molecules , have been studied as the three kinds of analytical probes. However, it is known that lots of dyestuffs are both toxic and carcinogenic .…”