2018
DOI: 10.1016/j.ijbiomac.2017.12.045
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Synthesis of novel benzodioxane midst piperazine moiety decorated chitosan silver nanoparticle against biohazard pathogens and as potential anti-inflammatory candidate: A molecular docking studies

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Cited by 53 publications
(23 citation statements)
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“…Since the specific and selective delivery and action of therapeutic agents became one of the most studied topics for improving current human healthcare practice, nanoparticles received tremendous attention regarding the design and development of novel and enhanced drug-delivery systems [ 78 ]. In particular, AgNP-based nanosystems were evaluated as suitable carriers of various therapeutic molecules, including anti-inflammatory [ 79 , 80 ], anti-oxidant [ 81 , 82 ], antimicrobial [ 83 , 84 ], and anticancer [ 32 , 85 ] biosubstances.…”
Section: Silver Nanoparticles For Drug-delivery Systemsmentioning
confidence: 99%
“…Since the specific and selective delivery and action of therapeutic agents became one of the most studied topics for improving current human healthcare practice, nanoparticles received tremendous attention regarding the design and development of novel and enhanced drug-delivery systems [ 78 ]. In particular, AgNP-based nanosystems were evaluated as suitable carriers of various therapeutic molecules, including anti-inflammatory [ 79 , 80 ], anti-oxidant [ 81 , 82 ], antimicrobial [ 83 , 84 ], and anticancer [ 32 , 85 ] biosubstances.…”
Section: Silver Nanoparticles For Drug-delivery Systemsmentioning
confidence: 99%
“…The nanoparticles were synthesized according to the protocol reported by Karthik et al 16 Briefly, a solution of chitosan (0.5 g) in 2% acetic acid and silver nitrate (AgNO 3 , 0.5 g) in deionized water were mixed. Exactly above 10 mL of chitosan and silver nitrate solutions were mixed in a boiling tube, and then, the mixture was kept in an autoclave at 120°C for 1 h. Then, the resultant clear orange-yellow solution was mixed with 0.5 g of N-(4chlorophenyl)-4-(2,3-dihydrobenzoijb]ij1,4]dioxine-2-carbonyl)piperazine-1-carbothioamide and sonicated for 3 h at 30°C.…”
Section: Synthesis Ofmentioning
confidence: 99%
“…Among many metals, synthesizing silver nanoparticle proved its tremendous applications in medicine and industries due to its microbial effect such as antifungal, antibacterial, antiparasitic, and larvicidal properties. Due to its may unrevealed benefits to human, need to process and tune the synthesis and access its properties of silver nanoparticles [14][15][16] including in the field of degenerative disease and cancer biology [17]. Many unrevealed plant components and its characteristics induce focused research scientists to look into that using the antioxidant character as basic property linked to many other properties such as anti-mutagenic, anti-carcinogenic, and anti-allergic [18].…”
Section: Introductionmentioning
confidence: 99%