Synthesis of novel fluoro 1,2,3-triazole tagged amino bis(benzothiazole) derivatives, their antimicrobial and anticancer activity

Benzothiazole-Based Bis-azo Cationic Fluorescent Dyes with Extended Conjugated Systems: Synthesis and Properties

“…Based on recently reported synthesis and application of dicationic dyes as bifunctional molecules [5,22,32,36], and in keeping with our former investigations on novel bifunctional hemicyanine dyes [37][38][39], here we report synthesis of 2aminobenzothiazoles-based dichromophoric cationic azo. In addition, several properties of the synthesized dyes such as electronic absorption and emission properties were studied, and their solvatochromic behavior were analyzed using Lippert-Mataga correlation and Reichardt-Dimroth's E T (N) equation [40,41].…”

“…In line with interest on benzothiazole cationic dyes for textiles dyeing [12], a diverse range of non-textile applications such as liquid crystal technology, reprography, nonlinear optics, and corrosion inhibitors have also been developed [13][14][15][16][17][18][19][20][21][22][23][24]. Recently, their biological activities such as antibacterial, antitumor, and antiviral activities have been reported as well [25][26][27][28][29][30][31][32][33][34][35].…”

An Overview of Recent Advances in the Applications of Click Chemistry in the Synthesis of Bioconjugates with Anticancer Activities

“…Benzothiazole derivatives due to different spectrum of pharmacological activity become a significant area of emphasis for the organic chemists . Recently, a merging of benzothiazole and 1,2,3‐triazole moieties has received considerable interest in improving the effectiveness of bioactive molecules with fascinating anti‐cancer activity …”

Synthesis and Anticancer Evaluation of Some Novel Thiophene, Thieno[3,2‐d]pyrimidine, Thieno[3,2‐b]pyridine, and Thieno[3,2‐e][1,4]oxazepine Derivatives Containing Benzothiazole Moiety

“…They are associated with various biological activities, for example, anticancer activity , because of inhibition of vital enzymes, namely, cytochrome P450 enzyme , EGFR tyrosine kinase , or COX‐2 enzyme . In addition, these derivatives are considered as antimicrobial , anti‐inflammatory , antioxidant , antitubercular , and antimalarial agents. Moreover, incorporation of thiophene nucleus at position 2 of benzothiazole gives rise to compounds possessing potent anticancer and antimicrobial activities.…”