Synthesis of Novel Pyridyl-Based Schiff Base and Its Coordination Behaviour with Ruthenium(II) and Zinc(II)

Abstract

High reactivity of the Schiff base product of p-toluidine with pyridine-2-carboxaldehyde was observed, leading to methyl group isomerization (immigration) to ortho-position followed by the dimerization reaction to form biphenyl system. This compound was identified and characterized using IR, ESI MS and NMR spectroscopic methods and its structure confirmed by XRD single crystal. The coordination behaviour of the Schiff base was examined using ruthenium(II) and zinc(II). Two metal complexes were only isolated and identified by Xray crystallography for ruthenium(II) and zinc(II). The coordination behaviour of both metals differs significantly, although both of them promote the oxidation reaction on one of the azomethine bond.

Synthesis and Therapeutic Potential of selected Schiff Bases: In vitro Antibacterial, Antioxidant, Antidiabetic, and Computational Studies

“…The aromatic band of the compounds at 228–280 nm is attributed to the benzene and pyridinyl rings π→π* transitions and the imine n→π* transition between 323 and 338 nm. All the physical and spectral data for the known compounds [37–42] agreed with the previously reported ones. The compounds were analyzed using mass spectrometry, and the results are shown in Figure S10–S12.…”

“…The aromatic band of the compounds at 228-280 nm is attributed to the benzene and pyridinyl rings π!π* transitions and the imine n!π* transition between 323 and 338 nm. All the physical and spectral data for the known compounds [37][38][39][40][41][42] agreed with the Scheme 1. Synthesis of L 1 -L 3 using the conventional method.…”