Synthesis of Novel Spiro Indolizidine Derivatives via 1,3-Dipolar Cycloaddition of Azomethine Ylide

Synthesis of 1,2,3-triazole-substituted 6,7-dihydroindolizin-8(5H)-one derivatives mediated by Selectfluor

“…15 Selectfluor has risen to prominence in recent years as a versatile commercially available reagent which is widely used in the synthesis of nitrogen-containing heterocycle. [16][17][18][19][20] In continuation of our work [21][22][23][24] on the synthesis of indolizin-8(5H)-one derivatives, in this paper, we reported the synthesis of 1,2,3-triazole and 1H-1,2,3-benzotriazole (BHT)-substituted 6,7-dihydroindolizin-8(5H)-one derivatives by the reaction of (E)-7-(arylmethylidene)-6,7dihydroindolizin-8(5H)-ones with 1,2,3-triazole and BHT in the presence of Selectfluor (Scheme 1).…”

An Efficient Synthesis of New Azomethine Ylide: 1-(Diaminomethyl-eneammonio)(aryl) methyl-4,4-dimethyl-2,6-dioxocyclohexan-1-ide under Solvent-Free Conditions

“…通 过文献查阅可以看到在目前报道的内鎓盐中, 以吡啶、 咪唑与巴比妥酸、麦氏酸、1,3-二羰基化合物等作为基 础的两性离子化合物是常见的, 这些结构的中, 负电荷 都在碳原子上, 而正电荷一般在氮原子上, 具体的结构 可以从图 1 中看到 [2～6] . 内鎓盐也是重要的合成中间体, 在一些 1,3-偶极环加成的反应中有重要的应用, 是合成 环状化合物重要方法之一 [7,8] . 王峰等 [9] 曾经报道了这类 化合物参与[3＋2]环加成反应的综述.…”