Synthesis of Perfluorocyclobutyl Aryl Ether-Containing ABA Triblock Copolymer via Click Chemistry

Abstract

Because of the unusual polymerization mechanism and normal high polymerization temperature of trifluorovinyl aryl ether monomers, it is difficult to synthesize perfluorocyclobutyl aryl ether (PFCB)-containing block copolymer via sequential addition of monomers. Here a coupling reaction via click chemistry to prepare PFCB-containing ABA triblock copolymer is reported. An azide-ended PFCB polymer, which was firstly prepared by end-modification of methyl-ended PFCB polymer, was coupled with alkynyl-ended polyethylene glycol via the azide alkyne Huisgen cycloaddition.

Synthetic of pH-Sensitive PEG-b-PHEMA(His) Polymers andthe Study of Micelle

“…点击化学 具有反应条件温和、产率可控、无副产物等优点, 已逐 步成为化学合成的重要方法, 其中具有代表性的铜作催 化剂的叠氮-炔环加成反应目前已被用在多嵌段聚合 物、树枝状分子等聚合物的合成上 [3] . 原子转移自由基 聚合反应(ATRP)同样具有分子量可控条件温和的特 点 [4] , 且产物的端基卤素原子极易转变成点击化学所需 要的 N 3 端基, 此外, ATRP 与点击化学都可用过渡金属 做催化剂, 因此, 结合两种聚合方式的一锅法已引起了 较多的重视 [5～8] .…”