Synthesis of Pharmacologically Active Indazoles and Its Analogues: A Review

Abstract

Studies on heterocyclic compounds are an evergreen branch of organic chemistry and attract the attention of chemists working not only in the field of natural products but also in synthetic chemistry. Indazole and its derivatives are one of the most vital heterocycles in drug molecules. Diversely substituted indazole derivatives have gained considerable attention in the field of medicinal chemistry due to their versatile biological activities. This mini review aims to abridge the recent (2011-2021 till date) advances in various methods for the synthesis of indazole derivatives. Moreover, the current developments in the biological activities of indazole-based compounds are also presented.