Synthesis of Phenanthro[9,10‐b]indolizidin‐9‐ones, Phenanthro[9,10‐b]quinolizidin‐9‐one, and Related Benzolactams by Pd(OAc)2‐Catalyzed Direct Aromatic Carbonylation

Yamashita, Satoshi; Kurono, Nobuhito; Senboku, Hisanori; Tokuda, Masao; Orito, Kazuhiko

doi:10.1002/ejoc.200801047

Cited by 56 publications

(26 citation statements)

References 89 publications

(38 reference statements)

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“…Br., Pergularia L. and Ficus L. [10,17]. These alkaloids exhibit interesting biological activities such as significant cytotoxic [18] and antitumor activities as well as anti-inflammatory [17], antimicrobial [8], antiviral [19], antiasthmatic [20], insecticidal and insect antifeedant [7,8,21] activities.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical composition and antifeedant activity of five Vincetoxicum taxa against Spodoptera littoralis and Leptinotarsa decemlineata

Güzel¹,

Pavela²,

İlçım³

et al. 2017

mpj

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Section: Introductionmentioning

confidence: 99%

Phytochemical composition and antifeedant activity of five Vincetoxicum taxa against Spodoptera littoralis and Leptinotarsa decemlineata

Güzel¹,

Pavela²,

İlçım³

et al. 2017

mpj

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“…The aromatic aldehydes 35a – h , 36a – h , 36p and 36j are commercially available. 1,2,3-Benzothiadiazole-7-carboxaldehyde ( 36i ) [32], 2,3,6,7-tetramethoxy-9-phenanthrenecarboxaldehyde ( 36k ) [33] and 3,6,7-trimethoxy-9-phenanthrenecarboxaldehyde ( 36l ) [33] were synthesized according to reported literatures. (6-Benzyloxy-2,3-dimethoxyphenanthren-9-yl)methanol ( 37 ), 6-hydroxy-2,3-dimethoxyphenanthrene-9-carboxylic acid methyl ester ( 38 ) and 3-hydroxy-6,7-dimethoxyphenanthrene-9-carboxylic acid methyl ester ( 39 ) were prepared according to our reported literature [34].…”

Section: Resultsmentioning

confidence: 99%

Discovery and SARs of Trans-3-Aryl Acrylic Acids and Their Analogs as Novel Anti- Tobacco Mosaic Virus (TMV) Agents

Wang

Meng

et al. 2013

PLoS ONE

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A series of trans-3-aryl acrylic acids 1–27 and their derivatives 28–34 were prepared and evaluated for their antiviral activity against tobacco mosaic virus (TMV) for the first time. The bioassay results showed that most of these compounds exhibited good antiviral activity against TMV, of which compounds 1, 5, 6, 20, 27 and 34 exhibited significantly higher activity against TMV than commercial Ribavirin both in vitro and in vivo. Furthermore, these compounds have more simple structure than commercial Ribavirin, and can be synthesized more efficiently. These new findings demonstrate that trans-3-aryl acrylic acids and their derivatives represent a new template for antiviral studies and could be considered for novel therapy against plant virus infection.

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“…The same group also reported the synthesis of N -protected staurosporinones and quinolizidine alkaloids by using Pd-catalyzed C–H carbonylation as a key step. 63 …”

Section: Incorporation With Carbon Monoxide/isonitrilementioning

confidence: 99%

Heterocycle Formation via Palladium-Catalyzed C-H Functionalization

et al. 2012

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Heterocyclic compounds are ubiquitous in natural products, pharmaceuticals, and agrochemicals. Therefore, the design of novel protocols to construct heterocycles more efficiently is a major area of focus in the organic chemistry. In the past several years, cyclization reactions based upon palladium-catalyzed C–H activation have received substantial attention due to their capacity for expediting heterocycle synthesis. This review discusses strategies for heterocycle synthesis via palladium-catalyzed C–H bond activation and highlights recent examples from the literature.

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Synthesis of Phenanthro[9,10‐b]indolizidin‐9‐ones, Phenanthro[9,10‐b]quinolizidin‐9‐one, and Related Benzolactams by Pd(OAc)₂‐Catalyzed Direct Aromatic Carbonylation

Cited by 56 publications

References 89 publications

Phytochemical composition and antifeedant activity of five Vincetoxicum taxa against Spodoptera littoralis and Leptinotarsa decemlineata

Phytochemical composition and antifeedant activity of five Vincetoxicum taxa against Spodoptera littoralis and Leptinotarsa decemlineata

Discovery and SARs of Trans-3-Aryl Acrylic Acids and Their Analogs as Novel Anti- Tobacco Mosaic Virus (TMV) Agents

Heterocycle Formation via Palladium-Catalyzed C-H Functionalization

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