Synthesis of phthalides from bis-propargyl ethers: use of Garratt–Braverman cyclization to construct the phthalans and IBX as a new reagent for subsequent oxidation

Panja, Arpita; Das, Eshani; Maji, Manasi; Basak, Amit

doi:10.1016/j.tetlet.2015.09.036

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Synthetic Routes To Phthalans1

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Cited by 9 publications

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“…The Basak group has made important contributions in this context. In particular, they have developed protocols for preparing aromatic phthalans such as 47 and 49 , heteroaromatic phthalans such as 51 , and aliphatic‐connected phthalans such as 53 (Scheme ).…”

Section: Synthetic Routes To Phthalansmentioning

confidence: 99%

Recent Advances in Phthalan and Coumaran Chemistry

et al. 2018

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Oxygen‐containing heterocycles are common in biologically active compounds. In particular, phthalan and coumaran cores are found in pharmaceuticals, organic electronics, and other useful medical and technological applications. Recent research has expanded the methods available for their synthesis. This Minireview presents recent advances in the chemistry of phthalans and coumarans, with the goal of overcoming synthetic challenges and facilitating the applications of phthalans and coumarans.

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Section: Synthetic Routes To Phthalansmentioning

confidence: 99%

Recent Advances in Phthalan and Coumaran Chemistry

et al. 2018

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“…The bis-propargyloxy ether derivatives constitute an interesting substrate for the yne-yne metathesis reactions 24,25 . These compounds have shown pharmacological and biological activities [26][27][28] . They also serve as key intermediates for the synthesis of many natural products including important antibiotics 29,30 and related polyaromatic compounds 31 .…”

Section: Introductionmentioning

confidence: 99%