“…Several compounds derived from pyridazines scaffold have been reported to possess a wide spectrum of biological activity such as the antidepressant, dopaminergic drug, monoamine oxidase inhibitor, anticonvulsant, GABA antagonist, muscarinic M1 partial agonist, and acetylcholinesterase (AChE) inhibitor . The chemistry of pyridazines is also dominantly useful as a pioneer for the preparation of other heterocycles, pi‐conjugated organic materials, and self‐assembled supramolecular architectures . Furthermore, two nitrogen atoms offer unique chemical and physicochemical properties such as the properties of conducting electricity, the most elevated dipolar moment, forming H‐bond interactions, coordination with metals, increasing the water solubility, and formation of crystalline for pyridazines .…”