Synthesis of polystyrene-bound perfluoroalkyl sulfonic acids and the application of their ytterbium salts in multicomponent reactions (MCRs)

Solvent-Free Addition Reaction of Allylzinc Bromide and Aldimines

“…The spectral data for compounds 3a, [16] 3b, [17] 3c, [18] 3d, [18] 3e, [19] 3i, [20] and 3j [17] are consistent with those reported in the literature. The physical and spectra data for compounds 3f, 3g, and 3h are as follows.…”

Multicomponent Mannich‐Like Reactions of Organometallic Species

“…Since those reports, organometallic Mannich reactions of this type have been intensively studied. The number of catalysts useable has grown considerably, and the scope has been extended by using SnCl 2 , [18] Bi(OTf ) 3 , [19] La(OTf ) 3 , [20] Montmorillonite KSF clay, [21] Selectfluor, [22] LiClO 4 , [23] [Bmim]BF 4 , [24] Sc(OTf ) 3 , [25] polystyrene-supported Yb salts, [26] a polystyrenesupported sulfonamide of glycine, [27] maleic acid, [28] BrS + Me 2 ,Br -, [29] 2,4,6-trichloro-1,3,5-triazine (TCT), [30] sulfamic acid, [31] camphorsulfonic acid (CSA), [32] ZrOCl 2 , [33] HClO 4 / SiO 2 , [34] phosphomolybdic acid (PMA)/SiO 2 , [35] CuI, [36] HfCl 4 (prenyl), [37] FeCl 3 , [38] PMA, [39] Bi(NO 3 ) 3 , [40] and In(OTf ) 3 . [41] The organometallic Mannich reaction with allyltributylstannane (22) has recently been exploited by Singh and coworkers in an elegant approach to isoindolinones 26 and tetrahydroisoquinolines 27.…”

“…Since those reports, organometallic Mannich reactions of this type have been intensively studied. The number of catalysts useable has grown considerably, and the scope has been extended by using SnCl 2 , Bi(OTf) 3 , La(OTf) 3 , Montmorillonite KSF clay, Selectfluor, LiClO 4 , [Bmim]BF 4 , Sc(OTf) 3 , polystyrene‐supported Yb salts, a polystyrene‐supported sulfonamide of glycine, maleic acid, BrS + Me 2 ,Br – , 2,4,6‐trichloro‐1,3,5‐triazine (TCT), sulfamic acid, camphorsulfonic acid (CSA), ZrOCl 2 , HClO 4 /SiO 2 , phosphomolybdic acid (PMA)/SiO 2 , CuI, HfCl 4 (prenyl), FeCl 3 , PMA, Bi(NO 3 ) 3 , and In(OTf) 3 …”

Nafion-Silica Nanocomposites: A New Generation of Water-Tolerant Solid Acids of High Efficiency

“…New polystyrene-bound perfluorosulfonic acids have recently been prepared and their ytterbium salts were used in multicomponent reactions to synthesize homoallylic amines and amides [115].…”