Framelike nanostructures consisting of interconnected,
ultrathin
ridges have attracted wide attention due to their high atomic utilization
efficiency among typical hollow architectures but are yet to be comprehensively
studied for photothermal applications. Herein, we report a facile
synthesis of AuAg yolk–shell cubic nanoframes (YSCNFs) with
tunable edge lengths, followed by the exploration of their photothermal
conversion and in vitro bacteria-killing performance,
together with our endeavors to understand the mechanism fundamentally.
By adopting the rationally screened capping agent docosyltrimethylammonium
chloride (DCTAC) throughout the stepwise synthesis, sharp cubic edges
could be generated and largely reserved, leaving the 5 nm cubic nanoframes
well standing. The increase in the cubic edge length leads to the
red shift of the major LSPR absorption peak toward the NIR region,
and abundant hot-spots appear at the frame corner and core surface
according to finite-difference time-domain (FDTD) simulation. The
photothermal conversion efficiency of YSCNFs can reach as high as
65.6% when a very low power density of 0.27 W cm–2 is used, which displays a powerful ability in combating multidrug-resistant
bacteria. The present study offers a systematic investigation of bimetallic
yolk–shell nanoframes including size/morphology control, photothermal
properties, mechanism studies, and antibacterial applications, which
could be of great value for the rational design of high-efficiency
photothermal nanomaterials for services to biomedicine.