Synthesis of Propargylic Alcohols and Biological Effects on Echinococcus multilocularis Metacestodes

Aza‐Michael Addition of Isatin and Phthalimide to Symmetrical Fumaric Esters in Ionic Liquid Media

“…7 Schiff bases and Mannich bases of isatin have antibacterial, [8][9][10] antifungal, [11][12][13] antiviral, [14][15][16] anti-HIV, [17][18][19] antiprotozoal, 20,21 and antihelminthic properties. 22,23 Isatin and its derivatives are also versatile starting materials for the synthesis of heterocyclic, non-cyclic and natural products. 24 For these reasons phthalimide, isatin and their derivatives are very important compounds in organic chemistry.…”

Solubility of a Pharmacological Intermediate Drug Isatin in Different Solvents at Various Temperatures

“…It is a yellow to red needle crystalline solid which has arose great attention in recent years due to their wide variety of biological activities and pharmacological studies as fungicides, 1 insecticides 2 , anticancer 3 , anticonvulsant 4 , anti HIV 5 , anti protozoal 6 , enzymatic 7 , antimicrobial 8 , antifungal 9 , anti-inflammatory 10 , anticonvulsant 11 and cytotoxic 12 and antioxidant 13 etc. Moreover, isatins are the synthetic precursors of some biologically important compounds 14,15 .…”

SOLVENT-FREE MICROWAVE MICHAEL ADDITION OF ISATIN AND ANILINE SCHIFF BASE OF ISATIN TO Α,β-Unsaturated ESTERS

“…In industries, isatin and its derivatives have been also used as UV light absorbers, blowing agents, flame-proofing agents, corrosion inhibitors, dry bleaches, disinfectants, and sanitizing agents. 8 Additionally, Schiff bases and Mannich basses of isatin were reported to possess antibacterial, 9 antifungal, 10 antiviral, 11 anti-HIV, 12 antiprotozeal, 13 and antihelminthic 14 activities. Michael addition is an important and useful reaction in organic synthesis.…”