“…Scientic teams from Russia and Brazil have obtained series of pyrimidine derivatives by reaction of polyuoroalkylated b-alkoxyenones with aminosubstituted pyrazoles, [97][98][99][100][101] triazoles, 100,102-104 imidazoles 101 and benzimidazoles. 105,106 It was shown that results are strongly dependent on reaction conditions. Thus, Goryaeva et al reported that aminopyrazoles as N,N-binucleophiles easily react with carbonyl compound 48 to form pyrimidinecarboxylates 49 with a good yield (Scheme 21).…”