2005
DOI: 10.1016/j.ejmech.2004.09.003
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Synthesis of Schiff bases of 4-(4-aminophenyl)-morpholine as potential antimicrobial agents

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Cited by 294 publications
(135 citation statements)
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“…Schiff bases are important class of compounds in medicinal and pharmaceutical field. They show biological applications including antibacterial [1][2][3][4][5][6], antifungal [3][4][5][6] and antitumor activity [7,8].…”
Section: Discussionmentioning
confidence: 99%
“…Schiff bases are important class of compounds in medicinal and pharmaceutical field. They show biological applications including antibacterial [1][2][3][4][5][6], antifungal [3][4][5][6] and antitumor activity [7,8].…”
Section: Discussionmentioning
confidence: 99%
“…Since crystal structures of HDAC3 and HDAC4 in complex with SAHA have not been determined so far, we used the crystal structure of HDAC8 in complex with SAHA which shows sequence similarity (46%) to HDAC4 [1], for docking experiments of compound 5 g , 5 h , and 6 k . We implemented control docking experiments with SAHA to the crystal structure of HDAC8 using AutoDock program [26,27].…”
Section: Molecular Docking Studiesmentioning
confidence: 99%
“…Presently cancer is the second leading cause of medical death in the US, and is anticipated to exceed heart diseases as the leading cause of death in the coming next few years [1]. According to Council of Health Service breast cancer is the most common cancer among Saudis with 15% of whole reported cancer.…”
Section: Introductionmentioning
confidence: 99%
“…They have made a considerable contribution to biological applications including antibacterial and antifungal diseases [1][2][3] . They can also act as ligands capable of interaction with various metal ions.…”
Section: Introductionmentioning
confidence: 99%