Synthesis of six-membered oxygenated heterocycles through carbon–oxygen bond-forming reactions

Electrophilic Functionalization of Non-Activated Olefins Catalyzed by Lewis Superacids

“…135 Generally, this reaction is promoted by electrophilic entities such as iodine, 136 phenylselenium chloride, 137 as well as mercuric 138 or palladium salts. 139 Nevertheless, a second step is needed in these processes to remove the electrophile.…”

Redox Economic Synthesis of TrisubstitutedPiperidones via Ruthenium Catalyzed Atom‐Economic Couplings of N‐Protected 1,5‐Aminoalcohols and Michael Acceptors

“…[1,2] (Figure 1). The piperidines resemble one of such important alkaloid cores mentioned for clinical and pre-clinical trials.…”

“…The piperidines resemble one of such important alkaloid cores mentioned for clinical and pre-clinical trials. [1,2] (Figure 1). Thus,catalytic synthetic approaches towards synthesis of these nitrogen heterocycles are highly sought after.…”

Vinyl Dihydropyrans and Dihydrooxazines: Cyclizations of Catalytic Ruthenium Carbenes Derived from Alkynals and Alkynones

“…[1] Their partially hydrogenated derivatives, for example, 3,4-dihydropyrans, [2] are interesting precursors for tetrahydropyrans [3] and glycals, [4] which are useful building blocks, particularly in carbohydrate chemistry. [1] Their partially hydrogenated derivatives, for example, 3,4-dihydropyrans, [2] are interesting precursors for tetrahydropyrans [3] and glycals, [4] which are useful building blocks, particularly in carbohydrate chemistry.…”