Synthesis of some 1'-(substituted phenyl)spiro[indole-3,4'-azetidine]-2(3H),2'-diones as potential fungicides

Green Synthesis of 1‐(1,2,4‐Triazol‐4‐yl)spiro[azetidine‐2,3′‐(3H)indole]‐2′,4′(1′H)‐diones as Potential Insecticidal Agents

“…To a solution of Schiff's base (0.01 mol) in DMF (10 mL), acetyl chloride [24] (0.01 mol) and triethylamine (0.01 mol) were added and the reaction mixture was stirred at room temperature for 24 h. The reaction mixture was poured into ice cold water and liberated compounds were extracted with chloroform. Solvent was evaporated under reduced pressure and recrystallized with ethyl acetate to give 4a in 60% yield, m.p.…”

(E)-5-[(2-Hydroxy-3-methoxybenzylidene)amino]-1,3,4-thiadiazole-2(3H)-thione

“…For hydrogen-bond motifs, see: Bernstein et al (1995). For the biological versatility of thione ligands, see, for example: Kumar et al (1988); Yadav et al (1989). For related structures, see: Zhang (2003); Kargar et al (2011Kargar et al ( , 2011aKargar et al ( , 2011b.…”

“…HK thanks PNU for the financial support. The biological versatility of compounds incorporating a thiadiazole ring is well known (Kumar et al, 1988;Yadav et al, 1989).…”

Synthesis, spectral, and antimicrobial studies of 1‐butyl‐3‐substituted‐4‐(2‐aryl‐1H‐indol‐3‐yl)‐2‐azetidinones

“…A mixture of 3-butyliminomethyl-2-arylindoles 3 (2 mmol) and triethylamine (4.2 mmol, 0.6 g) was dissoloved in tetrahydrofuran (25 mL) and cooled [2,20]. To this cooled solution, acetylchloride/ chloroacetyl chloride (2.4 mmol) was added slowly at 0 • C and the mixture was stirred for 24 h and then setaside for 48 h at room temperature.…”