Synthesis of Some Amino Acid Derivatives of Styrene<sup>1</sup>

Morris, L. R.; Mock, Richard A.; Marshall, C. A.; Howe, Joseph H.

doi:10.1021/ja01511a026

Cited by 58 publications

(23 citation statements)

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“…VBIDA was synthesized, with some modifications, according to a previously published procedure (Morris et al, 1959). A mass of 1.33 g (10 mmol) iminodiacetic acid and 660 mg (16.5 mmol) NaOH were dissolved in 20ml methanol/water 1/1 (v/v).…”

Section: Synthesis Of N-(4-vinyl)-benzyl Iminodiacetic Acid (Vbida)mentioning

confidence: 99%

An approach towards surface imprinting using the enzyme ribonuclease A

Kempe

Glad

Mosbach

1995

J of Molecular Recognition

206

119

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An adsorbent showing enhanced selectivity for the enzyme RNase A was prepared by a surface imprinting procedure based on metal coordination. A metal chelating monomer, N-(4-vinyl)-benzyl iminodiacetic acid, was polymerized onto methacrylate-derivatized silica particles in the presence of RNase A and metal ions. Lysozyme and RNase A were separated on the adsorbent used as stationary phase in high-performance liquid chromatography.

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Section: Synthesis Of N-(4-vinyl)-benzyl Iminodiacetic Acid (Vbida)mentioning

confidence: 99%

An approach towards surface imprinting using the enzyme ribonuclease A

Kempe

Glad

Mosbach

1995

J of Molecular Recognition

206

119

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“…The capillary was then left for 90 min at room temperature, and washed with acetonitrile. N-(Vinylbenzylimino)diacetic acid (2.5 mg), which was synthesized according to the previous report [11], was dissolved in 1 ml of distilled water. To the solution were added 7.5 l of N,N,N ,N -tetramethylethylenediamine and 15 l of 10% ammonium peroxodisulfate solution.…”

Section: Preparation Of Ida-modified Capillarymentioning

confidence: 99%

Preparation of an iminodiacetic acid-modified capillary and its performance in capillary liquid chromatography and immobilized metal chelate affinity capillary electrophoresis

Tsukagoshi

Shimadzu

Yamane

et al. 2004

Journal of Chromatography A

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“…We have synthesized a styrene derivative of IDA suitable for radical copolymerization with NIPAM. The synthesis was carried out according to Morris et al (1959) and the structure of the product was confirmed by proton NMR (data not shown).…”

Section: Nipam Copolymers With Metal Chelates For Affinity Precipitationmentioning

confidence: 99%

Affinity precipitation of proteins: design criteria for an efficient polymer

1998

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Affinity precipitation is fast emerging as a successful technique for the purification of proteins which can be introduced at an early stage of downstream processing. The technique applies the use of reversibly soluble-insoluble polymers which have either natural or synthetic origin. Apart from the successful use of some natural polymers, such as chitosan and alginate, the vast application of the technique depends upon the design of efficient synthetic polymers. In this laboratory, N-isopropylacrylamide (NIPAM) copolymers have been developed for metal chelate affinity precipitation of proteins. The copolymers of 1-vinylimidazole (VI) and iminodiacetic acid (IDA) with NIPAM were synthesized. The copolymers were thoroughly characterized with a view to designing an efficient soluble-insoluble polymer for metal chelate affinity precipitation of proteins.

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Synthesis of Some Amino Acid Derivatives of Styrene¹

Cited by 58 publications

References 0 publications

An approach towards surface imprinting using the enzyme ribonuclease A

An approach towards surface imprinting using the enzyme ribonuclease A

Preparation of an iminodiacetic acid-modified capillary and its performance in capillary liquid chromatography and immobilized metal chelate affinity capillary electrophoresis

Affinity precipitation of proteins: design criteria for an efficient polymer

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Synthesis of Some Amino Acid Derivatives of Styrene1

Cited by 58 publications

References 0 publications

An approach towards surface imprinting using the enzyme ribonuclease A

An approach towards surface imprinting using the enzyme ribonuclease A

Preparation of an iminodiacetic acid-modified capillary and its performance in capillary liquid chromatography and immobilized metal chelate affinity capillary electrophoresis

Affinity precipitation of proteins: design criteria for an efficient polymer

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Synthesis of Some Amino Acid Derivatives of Styrene¹