Synthesis Of Some Heterocyclic Compounds Derived From Ortho-Carboxybenzaldehyde

Abstract

In this work different heterocyclic compounds derivatives were synthesized using ortho-Carboxybenzaldehyde as a starting material which reacted with different aromatic amines to produce Schiff bases. These Schiff bases introduced in three types of reactions using different reagents (Chloroacetylchloride, Thio acetic acid, Malic anhydride and Phthalic anhydride) to give the target heterocyclic compounds four, five and seven heterocyclic compounds derivatives. The structure of these compounds identified by FT-IR and some of them by 1 H-NMR spectra

Synthesis, Characterization of Substituted 1,3-Oxazepine, Thiazolidine-4-one and Azetidine-2-one Using Benzimidazole as a Synthon

“…Properly substituted azitidine synthesis techniques have been developed with control of functional group and stereochemistry through the structural diversity of physiologically active β-lactam antibiotics (Hanoon et al, 2021). The 1,3-oxazepine is heterocyclic ring and contains two heterocyclic atoms (oxygen and nitrogen) (Tong, 2013), which have been found to exhibit biological activities (Maysaa and Moayed, 2022). The identification of 1,3-oxazepine's CNS action (Deng et al, 2016).…”