Synthesis of some pyrimidine derivatives via the reduction of schiff base type intermediates

Infrared spectra, thermogravimetric analysis and antifungal studies of noval Cr(III), Fe(III) and Cu(II) 2-methyl-quinazolinone complexes

“…The pale brown of 2-methyl-quinazolinone was prepared according to published method [20,21] by heating of 10 mmol 2-methyl-3,1-(4H)-benzoxazin-4-one and 25 mL of formamide for 3 h in oil bath and the reaction mixture was left aside at room temperature until the precipitation occurs, the solution was filtered under vacuum and the solid product was recrystallized from suitable solvent (ethanol).…”

Analgesic, anticonvulsant and anti-inflammatory activities of some synthesized benzodiazipine, triazolopyrimidine and bis-imide derivatives

“…Nien representative compounds 2, 3,7,8,10,12,14,15, and 17 were studied with respect to these properties. Initially the acute toxicity of the compounds was assayed determining their LD 50 .…”

“…In previous work we prepared certain substituted pyridines, pyrimidines derivatives and their pharmacological screening [1][2][3][4][5][6][7][8]. Pyrimidines and fused pyrimidines, being an integral part of DNA and RNA in it, play an essential role in several biological processes and have considerable chemical and pharmacological importance, particularly, the pyrimidine ring can be found in nucleoside antibiotics, antibacterials, cardio-vascular as well as agro chemical and veterin products [9][10][11][12][13][14][15][16][17].…”