Synthesis of symmetrical N,N′-alkylidene bis-amides catalyzed by silica coated magnetic NiFe₂O₄ nanoparticle supported polyphosphoric acid (NiFe₂O₄@SiO₂-PPA) and its application toward silver nanoparticle synthesis for electrochemical detection of glucose

Abstract

For the first time, a new and facile Ag@PM-b-B nanocomposite electrochemical sensor was successfully developed for the detection of glucose. Also, the magnetically recoverable catalyst was easily recycled at least ten times without significant loss of catalytic activity.

N,N,N′,N′-Tetramethylethylene-diaminium-N,N′-disulfonic acid trifluoroacetate and pyridinium-N-sulfonic acid hydrogen sulfate as highly effective dual-functional catalysts for the preparation of N,N′-alkylidene bisamides

“…[Py-SO 3 H][HSO 4 ] can also catalyze the reaction in this way. The mechanism is supported by the literature [33]. In fact, high efficacy of both catalysts can be attributed to dual functionality of them, and capability to activate the electrophiles and the nucleophiles to accelerate all steps of the reaction mechanism.…”

“…with aldehydes (1 eq.). Various catalysts have been reported for this synthesis, such as hydroxyapatite [28], phosphotungstic acid [29] [32], NiFe 2 O 4 @SiO 2 -PPA [33], CH 3 COCl [34], HPVAC-20 (heteropoly-11-tungsto-1vanadophosphoric acid supported on activated natural clay) [35], ZnCl 2 /SiO 2 [36] and sulfonated carbon/nanotitania composite (C/TiO 2 -SO 3 H) [37]. Nevertheless, many of the reported methods have restrictions such as, for example, long reaction times, moderate yields, harsh reaction conditions and the utilization of volatile and harmful organic solvents.…”

A Nanostructured Organic‐Inorganic Hybrid Material: Preparation, Characterization and Catalytic Performance for the Synthesis of N,N′‐Alkylidene Bisamides

“…A plausible mechanism, based on the literature, was proposed (Scheme ) ,. The acidic group of nano‐[DSPECDA][HSO 4 ] can accelerate the reaction by two roles: (i) activation of the carbonyl group of aldehyde for nucleophilic addition of amide (step 2), (ii) assistance for removing H 2 O (step 4), and (iii) activating the imine group for addition of amide to it (step 6).…”

“…with primary amides (2 eq. ); some catalysts have been reported for this synthesis, such as nano‐SnCl 4 .SiO 2 , B(OH) 3 , sulfonated carbon/nano‐titania composites, CuFe 2 O 4 , p ‐toluene sulfonic acid, heteropoly‐11‐tungsto‐1‐vanadophosphoric acid supported on natural clay, montmorillonite K10, NiFe 2 O 4 @KIT‐6@ZnO, 3D‐network polymer supported Bronsted acid ionic liquid based on calix‐resorcinarene, NiFe 2 O 4 @SiO 2 ‐PPA, molybdate sulfuric acid, and silica sulfuric acid …”

ONE POT PREPARATIONS N,N'-ALKYLIDENE BISAMIDE DERIVATIVES CATALYZED BY NANO-TiCL4.SiO2 WITH ANTIMICROBIAL STUDIES OF SOME PRODUCTS

“…5 Generally symmetrical alkylidene bisamides are synthesized by the direct reaction of aldehydes with the corresponding amides under suitable catalytic condition. In this topic, let us examine the various conditions of the catalysts such as sulfuric acid 6 , sulfonic acid 7 , triflic acid 8 , p-toluene sulfonic acid 9 , SiO 2 -MgCl 2 10 , hydrochloric acid 11 , CC-or DCMT activatd DMSO 12 , phosphotungstic acid 13 , boric acid 14 , silica coated magnetic NiFe 2 O 4 nanoparticle supported polyphosphoric acid 15 and p-toluenesulfonic acid. 16 Our studies towards the development of more efficient methods accompanied with higher yields for the synthesis of N,N'-Alkylidene bisamides in the presence of nano-TiCl 4 .SiO 2 .…”