Synthesis of Trifluoromethyl‐Containing 2,3‐Dihydrobenzofurans via a Formal [4+1] Annulation of In‐situ Generated o‐Quinone Methides and CF₃−Imidoyl Sulfoxonium Ylides

Abstract

A metal‐free [4+1] annulation of in‐situ generated ortho‐quinone methides (o‐QMs) and CF3‐imidoyl sulfoxonium ylides (TFISYs) has been achieved under mild conditions, which provides a facile and straightforward access to a variety of trifluoromethyl‐containing 2,3‐dihydrobenzofurans in moderate to excellent yields.