Synthesis of Triphenylamine-Imidazo[1,2-a]pyridine via Groebke–Blackburn–Bienaymé Reaction

Abstract

A series of triphenylamine-imidazo[1,2-a]pyridine were synthesized in moderate yields (57-67%) by Groebke-Blackburn-Bienaymé reaction (GBBR) under catalyst-and solvent green conditions. The molecules synthesized containing triphenylamine and imidazo[1,2-a]pyridines cores which are considered a privileged cores exhibited fluorescence and medicinal properties.

Recent advances on visible light Thiophene-based photoinitiators of polymerization

“…[302][303][304] To end, triphenylamine also exhibits biological activities, what could constitute an advantage for the design of bioactive photoinitiators. [305][306][307] In 2015, two star-shaped tris(4-(thiophen-2yl)phenyl)amine derivatives i.e. dye 17 and dye 18 were tested as photoinitiators of polymerization at 405 and 455 nm (See Figure 22).…”

Diaza-1,3-butadienes as Useful Intermediate in Heterocycles Synthesis

“…Several catalyst were used for his reaction, for example, L -proline [ 63 ], Yb(OTf) 3 [ 64 ], Candida antarctica lipase B (CALB) enzyme [ 65 ], NH 4 Cl [ 66 , 67 ], K-10 clay [ 68 ], AgOAc [ 69 ], thiamine hydrochloride [ 70 ], Sc(OTf) 3 [ 71 , 72 ], In(OTf) 3 [ 73 ], InCl 3 [ 74 ], and HClO 4 [ 75 , 76 ]. Nevertheless, catalyst and solvent-free conditions have also been reported [ 77 , 78 ].…”

Recent advances on visible light Triphenylamine-based photoinitiators of polymerization

“…Triphenylamine also exhibits biological activities that can be used for the design of bioactive photoinitiators. [201][202][203] Compared to the aforementioned dyes, triphenylamine-based photoinitiating systems exhibit advantages and disadvantages that are listed in the Table 1.…”