Synthesis of xanthan gum/trimethyl chitosan interpolyelectrolyte complex as pH-sensitive protein carrier

Elella, Mahmoud H. Abu; Hanna, Demiana H.; Mohamed, Riham R.; Sabaa, Magdy W.

doi:10.1007/s00289-021-03656-3

Cited by 28 publications

(7 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[58] Notice that the XRD pattern of BSA caped fluorescence nanoclusters displayed only two distinct diffraction peaks at 20°and 29.5°, which was similar to the XRD pattern of the native BSA, while the lower peaks (9°) vanished or decreased in the intensity due to increase in the degree of bonding between protein chain and nanoclusters and hence decreasing BSA crystallinity. [59,60] However, the XRD pattern failed to provide detailed compositional information about the nanoclusters, probably due to forming a pre-nucleating ultrafine nanocluster. However, crystallinity exhibited by the fluorescence nanoclusters may have resulted due to the BSA only.…”

Section: Chemistryselectmentioning

confidence: 99%

White Light Emitting Gadolinium Oxide Nanoclusters for In‐vitro Bio‐imaging

et al. 2022

View full text Add to dashboard Cite

Fluorescent probes are highly desirable for accurate diagnosis and play a crucial role in the optical imaging modality. Here, ultrafine (1.2 nm) nanoclusters of undoped gadolinium oxide were synthesized via a simple, one‐pot technique using water as the reaction medium. Prepared nanoclusters exhibit strong tuneable emission spanning from 400‐620 nm (extended visible region) with broad full width at half maximum of (FWHM) ∼140 nm, resulting in white light emission (WLE). Cytotoxicity studies revealed nearly 100 % cell viability encouraging its application in cell imaging. These nanoclusters possessed distinctive properties such as wide‐range pH stability, ionic tolerability, durable photostability, and anomalous colloidal stability (more than 24 months). This brief report uses white light‐emitting gadolinium oxide (Gd2O3) nanoclusters as an optical probe for in‐vitro fluorescence imaging.

show abstract

Section: Chemistryselectmentioning

confidence: 99%

White Light Emitting Gadolinium Oxide Nanoclusters for In‐vitro Bio‐imaging

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Similar to this, to improve the protein delivery through the gastrointestinal tract, the encapsulation and in vitro release of BSA which is within the interpolyelectrolyte complex (PEC) made from xanthan gum and trimethyl chitosan chloride (TMC) were investigated. It was learned that BSA was released without any degradation and was stable [66]. Xanthan-based hydrogels are also being studied for their potential use as scaffolds in tissue engineering and wound healing applications [58].…”

Section: Biomedical and Pharmaceutical Industrymentioning

confidence: 99%

A review presenting production, characterization, and applications of biopolymer curdlan in food and pharmaceutical sectors

Aquinas

Selvaraj

2021

Polym. Bull.

View full text Add to dashboard Cite

Curdlan is an exopolysaccharide, specifically a homopolysaccharide, with a high molecular weight that is made up entirely of monomeric glucose molecules connected by β-1,3-glycosidic bonds. Curdlan was first isolated in 1962 by Harada and his colleagues from Alcaligenes faecalis var myxogenes 10C3. Microbial synthesis of this curdlan is mainly associated with soil bacteria. Preliminary screening of curdlan-producing microorganisms is done on aniline blue media. The aniline blue positive microorganisms are subjected to submerged fermentation for the production of curdlan. To improve the yield of curdlan produced, various optimization techniques are employed such as Plackett–Burman, response surface methodology, and others. Curdlan can be characterized by its morphology, gel strength, its infrared, and magnetic resonances among many other characteristics. Due to its distinctive physicochemical and rheological properties, it has gained immense popularity in the food, biomedical, and pharmaceutical sectors. However, curdlan’s functionality can be improved by chemically modifying curdlan to obtain grafted curdlan, hydrogels, and nanocomposites which are discussed in detail herewith. Curdlan was authorized to be used in the food industry by the United States Food and Drug Administration in 1996 and also in 1989 in Taiwan, Japan, and Korea. Over the years, many patents using curdlan have also been filed from different parts of the world. This review provides information about its structure, biosynthesis, production strategies, optimization, characterization, applications, and patents. Graphic abstract

show abstract

“…Moreover, the authors investigated the antimicrobial property of the as-prepared hydrogels against Aspergillus niger and Staphylococcus aureus, and the reported findings confirmed the examined hydrogels could be used as antimicrobial protein carriers to deliver the proteins through the gastrointestinal tract. in this approach, Abu Elella et al [99] reported the fabrication of biodegradable interpolyelectrolyte complex hydrogel as a pH-sensitive protein carrier. They prepared interpolyelectrolyte complex based on XG and trimethyl-N-quaternized chitosan (TMC) to solve the drawbacks of the protein delivery through the GI tract.…”

Section: Bovine Serum Albuminmentioning

confidence: 99%

Synthesis and Potential Applications of Modified Xanthan Gum

Elella

2021

J. Chem. Eng. Res. Updates.

Self Cite

View full text Add to dashboard Cite

Designing high-performance adsorbents for wastewater treatment and antibacterial materials for food and biomedical applications and excellent drug carrier to prolong time retention of the therapeutic drug based on biodegradable polymers has gained more interest in recent years. Among these materials, xanthan gum, which is a natural polysaccharide and plays a vital role in various applications such as industry, enhanced oil recovery, water-based paints, pharmaceuticals, and personal care products because it has excellent properties such as biodegradability and non-toxicity. On the other hand, it has many affected limitations, including microbially attack, poor thermal and mechanical stability, and low surface area. So, in this review, we focused on the advanced modifications on xanthan gum and their applications in wastewater treatment, protein delivery, and designing antimicrobial materials.

show abstract

Synthesis of xanthan gum/trimethyl chitosan interpolyelectrolyte complex as pH-sensitive protein carrier

Cited by 28 publications

References 56 publications

White Light Emitting Gadolinium Oxide Nanoclusters for In‐vitro Bio‐imaging

White Light Emitting Gadolinium Oxide Nanoclusters for In‐vitro Bio‐imaging

A review presenting production, characterization, and applications of biopolymer curdlan in food and pharmaceutical sectors

Synthesis and Potential Applications of Modified Xanthan Gum

Contact Info

Product

Resources

About