Synthesis of β-phthalimido-alcohols via regioselective ring opening of epoxide by using reusable basic magnetic nano particles and their biological investigation

Abstract

In this work, regioselective ring opening of epoxides including aromatic and aliphatic epoxides to give β-phthalimido-alcohols has been reported.

A Nanostructured Organic‐Inorganic Hybrid Material: Preparation, Characterization and Catalytic Performance for the Synthesis of N,N′‐Alkylidene Bisamides

“…Performing chemical reactions in solvent‐free conditions has several benefits with respect to the classical solution protocols, which include: (i) greener reaction profile, (ii) no need to use volatile and harmful solvents as reaction media, (iii) reducing or preventing waste/by‐products, (iv) synthesis of products with higher yield in shorter time, (v) higher selectivity in many reactions, (vi) maximum transformation of reactants to aim product, (vii) fewer energy requirement to perform reaction, and (viii) easier work‐up and purification of product …”

[Fe3O4@SiO2@(CH2)3im]C6F5O as a New Hydrophilic and Task‐Specific Nanomagnetic Catalyst: Application for Synthesis of β‐Azido Alcohols and Thiiranes under Mild and Green Conditions

“…Because of high angle strain, their ring can be opened by various nucleophilic reagents and several 1,2‐disubstitued molecules will be produced. Phthalimide, indoles, phenols, thiols,, thiophenols,,, benzotriazole, alcohols,, acetic acid, H 2 O, azide, sulfide, cyanide and acid chlorides are examples of nucleophiles that have be used for this purpose. Some cyclic carbonate and sulfites were synthesized by silica‐immobilized homogeneous catalysts.…”