Abstract:w-Aminodithioester derivatives were obtained from thionolactams by reaction with an alkyl triflate followed by thiolysis with hydrogen sulfide. The presence of an electron-withdrawing group was required on the N1 position (p-nitrophenyl or benzoyl) to favor the ring opening of g-, d-and e-thionolactams. In the case of b-thionolactam, activation was provided by a CF 2 motif in C3 position Dithioesters have attracted considerable attention in recent years as versatile tools for organic synthesis. 1-5 Methods of … Show more
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