2013
DOI: 10.1007/s00044-013-0643-z
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Synthesis, physicochemical properties, antimicrobial and antioxidant studies of pyrazoline derivatives bearing a pyridyl moiety

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Cited by 23 publications
(17 citation statements)
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“…The selected golden yellow crystal (0.350 x 0.300 x 0.250 mm 3 ) of the compound was mounted on a Bruker AXS KAPPA APEX-II diffractometer at 293 (2) K with a graphite monochromatic Mo-Kα radiation (k = 0.71073 Å). The corrections for LP factors and empirical absorption were applied to the data.…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…The selected golden yellow crystal (0.350 x 0.300 x 0.250 mm 3 ) of the compound was mounted on a Bruker AXS KAPPA APEX-II diffractometer at 293 (2) K with a graphite monochromatic Mo-Kα radiation (k = 0.71073 Å). The corrections for LP factors and empirical absorption were applied to the data.…”
Section: Methodsmentioning
confidence: 99%
“…Easily tunable properties suit these electron rich nitrogen heterocycles to be used extensively as useful synthons in organic synthesis [1][2] as well as for medicinal applications [3][4]. These significant key motifs in heterocyclic chemistry are known not only from their pharmaceutical applications but also as materials showing excellent optical properties.…”
Section: Introductionmentioning
confidence: 99%
“…With the antitrypanosomal activity of chalcone hybrids in mind [8e11], we were intrigued to determine whether pyridylchalcones would also be active against this target. It was anticipated that pyridyl analogues would exhibit the same low toxicity shown by compounds containing the chalcone nucleus but with improved bioavailability [14]. The introduction of a pyridine group will reduce the lipophilicity of the molecule and increase water solubility, both of which should ease formulation.…”
Section: Introductionmentioning
confidence: 99%
“…The crucial role played by small heterocyclic molecules in drug design cannot be denied. These molecules act as highly functionalized scaffolds [7].…”
Section: Introductionmentioning
confidence: 99%