Synthesis, Spectral and Antibacterial Studies of Co(II), Ni(II), Cu(II) and Zn(II) Complexes with Acetone Acetyl hydrazone

Abstract

Hydrazone complexes of Co(II), Ni(II), Cu(II) and Zn(II) with acetone acetylhydrazone(AAH) ligand derived from the condensation of acetone and acetylhydrazine, containing N and O donor sites have been synthesized. The complexes are characterized by different physicochemical methods, elemental analysis, molar conductivity, IR, UV-Vis spectra and also magnetic measurements. The discussion of the out come data of the prepared complexes indicate that AAH behave as a neutral bidentate ligand. The electronic spectra as well as their magnetic moments suggest octahedral geometry for the bis-and tris-complexes, [M(AAH) 2 Cl 2 ], [M(AAH) 3 ](NO 3) 2 [M= Co(II), Ni(II), Cu(II), Zn(II)] and the mixed ligand complex [Ni(AAH) (Py) 2 Cl 2 ] and tetrahedral geometry for the mono complexes [M(AAH)Cl 2 ][M= Co(II), Cu(II), Zn(II)] and the other prepared mixed ligand complexes [Co(AAH)(Py) 2 ]Cl 2 and [Cu(AAH)(Py)Cl]Cl. The antimicrobial properties of the ligand and most of its complexes were studied using Gram-positive and Gram-negative bacteria. The metal complexes were found to have a moderate activity and Zn(II) complexes were the most active.