Synthesis, Spectral and Thermal Studies of New Rutin Vanadyl Complexes

Abstract

Complexes between oxovanadium (IV) cation and flavonoid derivatives were developed recently in order to increase the intestinal absorption and to reduce the toxicity of vanadium compounds. For these reasons, is interesting to investigate the complexation process between flavonoid rutin (Rut) and vanadyl cation in order to isolate new complexes. Two new complexes [VO(Rut)(H2O)2](SO4)0.5 2H2O and [VO(Rut)2] 4H2O have been obtained and characterized by elemental and thermal analyses and several spectroscopic techniques (ESI-MS, IR, UV-Vis, fluorescence). The studies concerning complex formation between vanadyl and rutin (Rut) performed in different solutions show the formation of mononuclear complexes with 1:1 and 1:2 metal to ligand stoichiometry.

Enhanced antioxidant activity, antibacterial activity and hypoglycemic effect of luteolin by complexation with manganese(ii) and its inhibition kinetics on xanthine oxidase

“…15,16 They can interact with metal ions via three domains including the dihydroxy group (3 0 -OH and 4 0 -OH) in the B ring, the 3-OH or 5-OH and the 4-CO groups in the C ring ( Fig. 1).…”

“…Despite increasing studies of various metal-avonoids complex and their biological activities, 11,15,17,18,21,22 research about the complexation between luteolin and manganese(II) cation has been limited. Therefore, the purpose of the present study was to examine the complex formation between luteolin and manganese(II) cation and conrm the complexation sites in luteolin by means of UV-visible spectroscopy, infrared spectroscopy, thermogravimetric analysis and elemental analysis.…”

“…Recently, the development of metal-based compounds with avonoids has been stimulated and the complexation of avonoids like quercetin, rutin and luteolin with a large number of metal cations such as Cu(II), 18 Zn(II), 11 V(II), 15 Mo(VI),…”

A semi-empirical study of flavone compounds with antioxidant efficiency

“…From these energy maps, it is concluded that good antioxidant efficiency of flavone is ensured by the increased number of OH groups on the skeleton and attenuation of the formation of phenoxyl radicals derived from these groups. The most stable radicals originating in the course of antioxidative action may be attributed to OH groups at the position C3 on the ring C, hydroxyl groups at mutual ortho positions at C3', C4' or C4' and C5' on the ring B and the various positions on the ring A (Uivarosi et al, 2010). The antioxidant efficiency of flavone also depends on the stability of the formed phenoxyl radical.…”

Mentha piperita protects against Cadmium induced oxidative renal damage by restoring antioxidant enzyme activities and suppressing inflammation in rats

“…In order to combat against Cd-induced oxidative renal damage, antioxidant phytochemicals may be the suitable antidotes because of their high antioxidant nature and low toxicity. The flavonoids are a family of phenolic compounds that possess a remarkable spectrum of biochemical and pharmacological activities like antibacterial, antiviral, antiinflammatory, antiallergic, antithrombotic, antimutagenic, antineoplastic, as well as neuroprotective properties [14]. Mentha piperita (Lamiaceae), the peppermint (mint) plant is an aromatic perennial herb cultivated in most part of the world, have traditionally been used in folk medicine.…”