Synthesis, spectral, electrochemical and DNA binding properties of ruthenium (III) complexes of Schiff bases containing N,O donor atoms

Puthilibai, G.; Vasudhevan, S.

doi:10.1016/j.matpr.2020.07.008

Cited by 11 publications

(5 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, the Ru 3+ complex's ( 3 ) EAS demonstrated one band at 540, which could be allocated to 2 T 2g → 2 A 2g transition, while the charge transfer transition (LMCT) from the chelator's filled HOMO orbital to the individually busied ruthenium t2 orbital (LUMO) may be responsible for the band at 420 nm. The position of this band is similar to that of other octahedral structured Ru 3+ complex 64,65 . The hexa‐chelated Co 2+ cation (octahedral crystal field) possesses 4 F ground state that split into 4 T 2g 4 T 1g (P), and 4 A 2g consequently with expected spin‐allowed transitions (v 1 ) 4 T 1 g(F)→ 4 T 2g (F), (v 2 ) 4 T 1 g(F)→ 4 A 2g and (v 3 ) 4 T 1 g(F)→ 4 T 1g (p) 64,66 .…”

Section: Resultssupporting

confidence: 66%

See 1 more Smart Citation

New homo‐bimetallic complexes of dihydrazone‐oxime ligand incorporating isatinic moiety: Preparation, characterization, theoretical, microbicidal, and anticancer investigation

Ebrahium

2023

Applied Organom Chemis

View full text Add to dashboard Cite

A new series of dihydrazone-oxime ligand's homo-bimetallic complexes of for-butan-2-ylidene)hydrazono)indolin-2-one (HL,1) with the salts of Fe 3+ , Ru 3+ , Co 2+ , Cu 2+ , Mn 2+ , Zn 2+ , and UO 2 2+. The newly prepared compounds' structure was elucidated based on traditional techniques such as molar conductance, magnetic measurements, elemental, thermogravimetric (TGA) analyses, and mass spectrometry, as well as spectroscopic tools such as electronic absorption, infrared, nuclear magnetic resonance, mass, and electron spin resonance spectra. The values of complexes molar conductance in DMSO indicated that they

show abstract

Section: Resultssupporting

confidence: 66%

“…The position of this band is similar to that of other octahedral structured Ru 3+ complex. 64,65 The hexa-chelated Co 2+ cation (octahedral crystal field) possesses 4 F ground state that split into 4 T 2g 4 T 1g (P), and 4 A 2g consequently with expected spin-allowed transitions (v 1 ) 4 T 1 g(F)! 4 T 2g (F), (v 2 ) 4 T 1 g(F)!…”

Section: Ft-ir Spectramentioning

confidence: 99%

New homo‐bimetallic complexes of dihydrazone‐oxime ligand incorporating isatinic moiety: Preparation, characterization, theoretical, microbicidal, and anticancer investigation

Ebrahium

2023

Applied Organom Chemis

View full text Add to dashboard Cite

show abstract

“…The experiments involving the interaction of the complexes with DNA were carried out in Tris buffer (5 mM Tris and 50 mM NaCl, pH 7.2). Absorption titration experiment was performed by maintaining the metal complex concentration constant (2 µM) and varying the concentration of nucleic acid from (0 to 20 µM) [9][10][11][12][13][14][15][16][17][18].…”

Section: Dna Binding Experimentsmentioning

confidence: 99%

“…The activity increases with increase in concentration of test solution containing the new complexes. The different compounds exhibit microbial activity with small variations against the bacterial species and this difference in activity could be attributed to the impermeability of the cell of the microbes or differences in the ribosomes of the microbial cells [16]. Although the complexes are active, they did not reach the effectiveness of the conventional bacteriocide ampicillin.…”

Section: Antibacterial Investigationmentioning

confidence: 99%

Synthesized and hypothesized schiff base ligand and its metal(II) complexes DNA binding mode

Puthilibai,

Devatarika,

Haewon

et al. 2023

Bull. Chem. Soc. Eth.

View full text Add to dashboard Cite

ABSTRACT. Metal complexes play an important role in agriculture, pharmacology, medicine, and industrial chemistry. Schiff base metal compounds are the fusion products of propene and aldehydes, require a metal surrounded by an ion or cluster of molecules to form. Metal complexes of Co(II), Ni(II), Cu(II), and Zn(II) have also been created. Elemental analysis is used to analyses the structure and related compounds of the produced Schiff base ligand. According to deoxyribose nucleic acid (DNA) binding tests, Schiff base metal(II) complexes attach to DNA in an intercalative form with weak covalent connections. The predicted DNA binding mode supports an increase in the complexes' binding activity in the presence of newly generated ligand. The cleavage activities of the DNA were recorded using gel-electrophoresis in the presence and absence of the complexes. The findings of the cleavage experiment show that all of the produced chelates can successfully cut DNA. KEY WORDS: Schiff base ligand, DNA, Metal(II) complex, Hetero-ligand cobalt(II), Aldehydes Bull. Chem. Soc. Ethiop. 2023, 37(5), 1133-1139. DOI: https://dx.doi.org/10.4314/bcse.v37i5.6

show abstract

“…These compounds characterized by their versatile coordination properties and fascinating biological activities, have garnered substantial attention in recent years. Schiff-base metal complexes have good biological behaviour like dissecting their interactions with biomolecules, cellular uptake mechanisms and intracellular behaviour, seek more attention to researchers [9][10][11][12][13][14][15]. In this study, we conduct an investigation into Schiff-base metal complexes, focusing specifically on those formed from amino adamantane and thiophene derivatives in combination with nickel(II), copper(II) and cobalt(II) as central metal ions.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Spectral Characterization, Antibacterial and Anticancer Evaluation of Novel Isoniazid based Schiff Base Ligand derived Transition Metal Complexes

Suganya,

Puthilibai

2024

ajc

View full text Add to dashboard Cite

A novel isoniazid based Schiff base ligand was synthesized by the condensation of 5-acetyl-N-(adamantan-2-yl)thiophene-2-carboxamide (1 mmol) and isoniazid (1 mmol). Metal complexes were prepared by reacting the Schiff base with metal(II) chloride (M = Ni2+, Cu2+ and Co2+), formed the novel metal coordination compound. The synthesized ligand and metal complexes were characterized by 1H NMR, mass spectral, UV-visible, IR & EPR spectral studies, themogravimetric analysis, cyclic voltametry and were screened with both Gram-positive and Gram-negative bacterias to evaluate the antibacterial activity by disc diffusion method. The zone of inhibition of the antibacterial assay demonstrated that all the three metal(II) complexes are active against the four bacterias, showed increased activity with increase in concentration and is more active against S. aureas at all concentrations. The systhesized complexes were also evaluated for its anticancer activities, only Ni(II) and Co(II) complexes showed the moderate levels of cytotoxicity activity.

show abstract

Synthesis, spectral, electrochemical and DNA binding properties of ruthenium (III) complexes of Schiff bases containing N,O donor atoms

Cited by 11 publications

References 33 publications

New homo‐bimetallic complexes of dihydrazone‐oxime ligand incorporating isatinic moiety: Preparation, characterization, theoretical, microbicidal, and anticancer investigation

New homo‐bimetallic complexes of dihydrazone‐oxime ligand incorporating isatinic moiety: Preparation, characterization, theoretical, microbicidal, and anticancer investigation

Synthesized and hypothesized schiff base ligand and its metal(II) complexes DNA binding mode

Synthesis, Spectral Characterization, Antibacterial and Anticancer Evaluation of Novel Isoniazid based Schiff Base Ligand derived Transition Metal Complexes

Contact Info

Product

Resources

About