2022
DOI: 10.2174/2211352519666211104090749
|View full text |Cite
|
Sign up to set email alerts
|

Synthesis, Spectral Investigations, Biological Potential and Molecular Docking Study of Novel Schiff Base and its Transition Metal Complexes

Abstract: Aim: The present study was designed to synthesize novel Schiff bases and their metal complexes with promising antimicrobial and anti-angiogenic potential. Background: Currently, drug resistance has been seen in a diverse range of microbes, which is considered a major threat to widespread infectious diseases. Therefore, it is essential to investigate novel therapeutic molecules with broad-spectrum activities. Method: The novel Schiff base ligands were synthesized by using a condensation reaction of eth… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2022
2022
2024
2024

Publication Types

Select...
2

Relationship

1
1

Authors

Journals

citations
Cited by 2 publications
(1 citation statement)
references
References 44 publications
0
1
0
Order By: Relevance
“…Due to the presence of azomethine linkage (>C=N-), complexes have been found to inhibit microbial growth. Different mechanisms have been suggested including the inhibition of cell wall synthesis and loss of the bioactivity of fundamental enzymes, such as dihydropteroate synthase [49,50]. In the current study, the examined ligand and their metal complexes possess strong anti-microbial activities.…”
Section: Antimicrobial Assaymentioning
confidence: 82%
“…Due to the presence of azomethine linkage (>C=N-), complexes have been found to inhibit microbial growth. Different mechanisms have been suggested including the inhibition of cell wall synthesis and loss of the bioactivity of fundamental enzymes, such as dihydropteroate synthase [49,50]. In the current study, the examined ligand and their metal complexes possess strong anti-microbial activities.…”
Section: Antimicrobial Assaymentioning
confidence: 82%