Synthesis, spectroscopic and Hirshfeld surface analysis and fluorescence studies of (2E,2′E)-3,3′-(1,4-phenylene)bis[1-(4-hydroxyphenyl)prop-2-en-1-one] N,N-dimethylformamide disolvate

Abstract

In the bis­chalcone mol­ecule, the central benzene and terminal hy­droxy­phenyl rings form a dihedral angle of 14.28 (11)° and the central C=C double bond adopts a trans conformation. In the crystal, the title mol­ecule and solvate are linked by O—H⋯O hydrogen bonds.

Elucidating bis-pyrimidines as new and efficient mushroom tyrosinase inhibitors: synthesis, SAR, kinetics and computational studies

“…The spectroscopic data of bis-chalcones (1C-6C & 8C) are already reported in the literature. [53][54][55][56][57][58][59] Nevertheless, the spectral data of all the newly synthesized target compounds is given in ESI † le.…”