“…In addition, Leu325, Ala321, Ala108, and Ala176 established π-alkyl interactions while Asp172 formed a halogen (fluorine) interaction [ 27 , 28 ]. The best-docked pose of [(Ris) (PA)]-dopamine revealed that the amino acid residues, including Thr142, Ala185, His393, and Tyr408, formed hydrogen bond interactions, Val115 and Phe389 established π-alkyl interactions, Trp386 established π-sigma, and Cys118 formed a halogen (fluorine) interaction [ 29 , 30 ]. The best-docked pose of the [(Ris) (PA)]-adrenergic receptor interaction revealed that the amino acid residues Val414, Asp206, Asp131, and Ser218 formed hydrogen bond interactions, while Phe398, Phe423, and Cys135 established π-alkyl interactions, and Val132 and Ser214 established π-sigma and halogen (fluorine) interactions, respectively.…”