Synthesis, Spectroscopic Studies, Antibacterial Activity, and Colorimetric Evaluation of the Time-Killing Assay for Newly Synthesized Chalcones Using Resazurin

Synthesis and screening of novel lipophilic diarylpropeones as prospective antitubercular, antibacterial and antifungal agents

“…Antimicrobial agents of both synthetic and natural origin can provide the means to treat infections caused by microorganisms thus saving millions of lives. Diarylpropenones commonly called as chalcones has biological activities against microbial [4][5][6][7][8][9][10][11][12] and tubercular infections [13], oxidative stress 14], cancer, fungal infections, liver diseases, bronchitis [15][16][17], antimalarial [18] etc.,. Chalcone is chemically 1,3-diaryl-2-propen-1-one in which the two aromatic rings are joined by a three-carbon ,β-unsaturated carbonyl system, representing a class of flavonoids that occurs naturally in fruits and vegetables.…”