Synthesis, structural investigations, and <i>in vitro</i> biological activity of Co(II) and Fe(III) mixed ligand complexes of 1,10‐phenanthroline and 2,2′‐bipyridine

Tigineh, Getinet Tamiru; Abiye, Melese; Melese, Aklilu; Abebe, Atakilt

doi:10.1111/cbdd.13967

Cited by 6 publications

(2 citation statements)

References 45 publications

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“…This dispersion ensures the possible transition of electrons from the HOMO to LUMO levels. The following equations describe the calculated parameters: [ 69 ] …”

Section: Resultsmentioning

confidence: 99%

A perception into binary and ternary copper (II) complexes: synthesis, characterization, DFT modeling, antimicrobial activity, protein binding screen, and amino acid interaction

et al. 2023

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Ensuring healthy lives and promoting well-being for all at all ages is the third goal of the sustainable development plan, so it was necessary to identify the most important problems that threaten health in our world. The World Health Organization declared that antibiotic resistance is one of the uppermost global public health threats facing humanity and searching for new antibiotics is slow. This problem can be approached by improving available drugs to combat various bacterial threats. To circumvent bacterial resistance, three copper(II) complexes based on the pefloxacin drug were prepared and characterized using analytical, spectroscopic, and thermal techniques. The resulting data suggested the formation of one octahedral binary and two distorted square pyramidal ternary complexes. Fluorescence spectra results revealed the formation of a turn-on fluorophore for amino acid detection. Computational calculations investigated quantum and reactivity parameters. Molecular electrostatic potential profiles and noncovalent bond interaction-reduced density gradient analysis indicated the active sites on the complex surface. The complexes were subjected to six microbial species, where the octahedral binary complex provoked its antimicrobial potency in comparison with ternary complexes. The enhanced antimicrobial activity against gram-negative bacterium E-coli compared to gentamicin was exhibited by the three complexes. Docking simulation was performed based on the crystal structure of E. coli and S. pneumoniae receptors using 5I2D and 6O15 codes. The binary complex exhibited a potent fitness score with 5I2D (TBE = − 107 kcal/mol) while ternary complexes displayed the highest docked score of fitness with 6O15.

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“…This dispersion ensures the possible transition of electrons from the HOMO to LUMO levels. The following equations describe the calculated parameters: [ 69 ] …”

Section: Resultsmentioning

confidence: 99%

A perception into binary and ternary copper (II) complexes: synthesis, characterization, DFT modeling, antimicrobial activity, protein binding screen, and amino acid interaction

et al. 2023

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“…Since the particle size is related to the sintering temperature and the holding time of the peak temperature, SEM is used to observe the microstructure of sintered silver under different process conditions, and the particle size is counted according to the linear interpolation method [6]. With the increase of sintering current or energization time, the size of silver particles after sintering increases significantly.…”

Section: Introductionmentioning

confidence: 99%

Application Preparation of High‐Performance Iron‐Based Powder Metallurgy Sintered Materials in Sports Industry

Bai-fang

2022

Journal of Nanomaterials

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Nowadays, the rapid development of sports science and technology has brought about the vigorous development of the sports industry, which is worth studying for a long time in the future. This article aims to use metallurgical sintering technology to prepare high-performance iron-based powder materials and apply them in the traditional sports industry to produce new sports equipment. This article proposes a metallurgical sintering method, that is, the use of a process of powdered iron-containing materials through a series of operations to finally obtain a new agglomerate and to obtain the required new physical and mechanical properties of materials or products. A new type of material is made and used in the traditional sports industry to meet the high-quality needs of sports equipment in the current era. According to survey statistics, my country’s sports industry has been developing rapidly in the past five years. It has increased from 1,901.13 billion yuan in 2016 to 2,869.35 billion yuan in 2020. Sports investment and financing events have also dropped from 313 to 105, but the entire sports industry’s investment is getting bigger and bigger. The number of employees in the national sports industry has also exceeded the 2 million mark. In the future, the sports industry is also an industry with great potential for development.

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Molecular Docking, DFT, and Antibacterial Activity Study of a Newly Synthesized Mixed Ligand Complex of Co(II), 1,10-Phenanthroline, Adenine and Acetamide

et al. 2023

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Synthesis, structural investigations, and in vitro biological activity of Co(II) and Fe(III) mixed ligand complexes of 1,10‐phenanthroline and 2,2′‐bipyridine

Cited by 6 publications

References 45 publications

A perception into binary and ternary copper (II) complexes: synthesis, characterization, DFT modeling, antimicrobial activity, protein binding screen, and amino acid interaction

A perception into binary and ternary copper (II) complexes: synthesis, characterization, DFT modeling, antimicrobial activity, protein binding screen, and amino acid interaction

Application Preparation of High‐Performance Iron‐Based Powder Metallurgy Sintered Materials in Sports Industry

Molecular Docking, DFT, and Antibacterial Activity Study of a Newly Synthesized Mixed Ligand Complex of Co(II), 1,10-Phenanthroline, Adenine and Acetamide

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