Synthesis, structural studies and computational evaluation of cyclophanes incorporating imidazole-2-selones

Mageed, Ahmed Hassoon; Al-Ameed, Karrar

doi:10.1039/d3ra02913a

Cited by 4 publications

(1 citation statement)

References 55 publications

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“…[6,[9][10][11][12][13] Recently, there has been an increasing interest in the use of NHC complexes of late transition metals such as Cu, Ag, Au, Pd, or Pt in bioinorganic and medicinal chemistry as antibacterial or anticancer agents. [2,[4][5][6][14][15][16][17][18][19][20][21] In 1993, Arduengo reported the first synthesis of a silver-NHC complex. [22] However, it was not until 1998 that a significant breakthrough was made by Lin et al, [23] who demonstrated that Ag(I)-NHC complexes can serve as highly efficient transfer reagents for the synthesis of other NHC-metal complexes.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Anticancer Activities of some Ag(I) Complexes Involving N‐Heterocyclic Carbene Ligands

Mageed,

Hadi

2024

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A new study focused on the synthesis of silver(I)‐N‐heterocyclic carbene complexes. The mono‐Ag(I)‐NHC complexes were successfully synthesized in high yield using a direct complexation method, which involved an excess of Ag2O and imidazolium salts (R= butyl, methylacetate) in dichloromethane. The bis‐Ag(I)‐NHC complexes, on the other hand, were synthesized using a 1 : 2 ratio of Ag2O and imidazolium salts. The ligands and resulting complexes were thoroughly characterized using analytical techniques such as FT‐IR, NMR spectroscopy, LC–MS and elemental analysis. Subsequently, the synthesized complexes were tested against MCF7 breast cancer cells. The results of the study highlighted the remarkable anticancer potential exhibited by the Ag(I)‐NHC complexes against breast cancer cells. Interestingly, it was observed that the mono Ag(I) NHC complexes demonstrated greater potency, with IC50 values ranging from 5 to 13.5 μg/mL, when compared to their bis‐Ag(I)‐NHC counterparts.

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Section: Introductionmentioning

confidence: 99%

Synthesis and Anticancer Activities of some Ag(I) Complexes Involving N‐Heterocyclic Carbene Ligands

Mageed,

Hadi

2024

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Synthesis and properties of a novel ionic liquid copolymer shale inhibitor

Bai,

Chen,

et al. 2023

J of Applied Polymer Sci

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As oil reserves in shallow wells continue to deplete, the drilling industry must shift its focus toward extracting oil from deeper and more complex formations. Water‐based drilling fluid inhibitors are currently limited in their ability to withstand high temperatures. In the current work, for the first time, the application of 1‐vinyl‐3‐ethylimidazolium bromide salt‐allyl alcohol polyoxyethylene ether‐2‐acrylamide‐2‐methylpropanesulfonic acid (PIAA) as the shale inhibitor is reported. The incorporation of ionic liquids has made PIAA promising to be an effective shale inhibitor for high‐temperature‐tolerant water‐based drilling fluids. The high‐temperature resistance (300°C) of PIAA was verified through thermogravimetric test. Through mud ball, shale rolling recovery, and linear swelling experiments, we found that PIAA yielded the lowest swelling rate (27.3%) in the 24‐h linear swelling rate test, as compared to HMA‐15 (46.1%) and FA‐367 (31.2%). This confirmed the superior corrosion inhibition performance of PIAA. In addition, we investigated the inhibition mechanism using Zeta potential and other tests. Bentonite inhibition can be achieved through the coating of bentonite particles by PIAA, which effectively plugs shale pores, neutralizes negative charges on the surface of bentonite particles, and adsorbs them onto particle surfaces. Overall, PIAA has excellent high‐temperature resistance and inhibition properties.

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Synthesis, and study biological activity of CuI complexes involving imidazole-2-selones as ligands

Mageed,

Ali

2023

Journal of Organometallic Chemistry

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Synthesis, structural studies and computational evaluation of cyclophanes incorporating imidazole-2-selones

Abstract: Cyclophanes incorporating o-xylylene or mesitylene-m-cyclophane linked-selone groups are mutually syn in both solid state and solution. While, m-xylylene or p-xylylene cyclophanes linked-selone groups show syn and anti conformations in the solution.

Cited by 4 publications

References 55 publications

Synthesis and Anticancer Activities of some Ag(I) Complexes Involving N‐Heterocyclic Carbene Ligands

Synthesis and Anticancer Activities of some Ag(I) Complexes Involving N‐Heterocyclic Carbene Ligands

Synthesis and properties of a novel ionic liquid copolymer shale inhibitor

Synthesis, and study biological activity of CuI complexes involving imidazole-2-selones as ligands

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