Synthesis, Structure and Reactions of Organometallic Derivatives of Oximes

Abstract

Organometallic derivatives of oximes were reviewed. These derivatives were selected and presented according to the place of the metal in the periodic table. Formation and reactions of disalts of oximes of type RC(CHMR′)=NOM (R, R′ = H, alkyl, aryl) and monosalts of oximes of type RC(CHMR′)=NOR″ (R″ = alkyl, aryl, M = alkali metal) were presented. Synthesis and reactions of silicon, germanium, tin, phosphorus containing oximes were included too. Beside this, oxime metal derivatives (for example, oxime palladacycles) as valuable catalysts in organic synthesis were described. In addition, oxime metal complexes exhibit wide spectrum of biological activity. Using of technetium‐99m hexamethylpropyleneamineoxime (Ceretec TM ) and related oxime complexes in diagnosis was described. Silicon and tin oxime complexes as excellent agrochemical agents were presented. Some cobalt, platinium and silicon containing oxime ethers exhibit high antitumor and cytotoxic activity and will be perspective targets for the further investigations. Introduction Synthesis, Structure and Reactions of Organometallic Derivatives of Oximes Conclusions