Synthesis, Urease Inhibition, Antimicrobial and Antioxidant Studies of 3,4,5-Trihydroxy Benzoic Acid Derivatives

Mondal, Kalyan K.; Sharma, Shashi; Kakkar, Saloni; Khatkar, Anurag

doi:10.35652/igjps.2018.1220

Cited by 2 publications

(2 citation statements)

References 11 publications

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“…The beneficial health effects of hesperidin, one of the main bioflavonoids of the food industry, involve antioxidant, anti-inflammatory, antibacterial, anti-cancer, and antimicrobial properties (Pyrzynska, 2022). Vanillic acid is a valuable phenolic acid that draws attention with its antimicrobial, antioxidant, anti-cancer, antidiabetic, anti-inflammatory, antiulcer, and antinociceptive effects beyond its flavoring feature (Malik et al, 2023). Gentisic acid is an important phenolic acid with beneficial therapeutic effects were presented as anti-inflammatory, antimicrobial, hepatoprotective, antigenotoxic, and neuroprotective, remarkably antioxidant activities in in vivo and in vitro studies (Abedi et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

A study on phytochemical composition, antioxidant, and anti-cancer activities of Gingko biloba L.

YILMAZ,

DEVECİ,

TEL-ÇAYAN

2023

Comm. J. Biol.

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The study aims to investigate the phytochemical composition, antioxidant potential, and anti-cancer activities of Ginkgo biloba L. leaf methanol extract. In this study, the phytochemical compounds, total phenolic and flavonoid contents of G. biloba leaf methanol extract were investigated. Additionally, antioxidant and anti-cancer activities [against HT-29 (human colon cancer line), HeLa (human cervical cancer line), and HEK-293 (human embryonic kidney cell line)] were assayed. The main phytochemical compounds were identified as gallic (0.94±0.01 mg/g), p-hydroxy benzoic (0.71±0.01 mg/g), and protocatechuic (0.60±0.02 mg/g) acids in G. biloba leaf methanol extract by HPLC. The total phenolic and total flavonoid contents were measured as 71.20±0.42 µg GAE/mg extract and 13.24±0.35 µg QE/mg extract, respectively. The high antioxidant activity was found in ABTS•+ assay (89.04±0.71%) while moderate antioxidant activity was observed in DPPH• (43.31±0.75%), metal chelating (49.04±0.49%), CUPRAC (absorbance: 0.85±0.01), and phosphomolybdenum (absorbance: 1.16±0.02) assays at 400 µg/mL. The IC50 values of G. biloba leaf methanol extract on HT-29, HeLa, and HEK-293 cell lines were recorded as 406.70±1.55, 84.86±0.98, and >800 µg/mL, respectively. The present study features a new addition to the antioxidant and anti-cancer properties of the therapeutically valuable G. biloba with its phytochemical content.

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Section: Discussionmentioning

confidence: 99%

A study on phytochemical composition, antioxidant, and anti-cancer activities of Gingko biloba L.

YILMAZ,

DEVECİ,

TEL-ÇAYAN

2023

Comm. J. Biol.

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“…FT-IR (cm –1 ): 2800–3400 (O–H stretching); 1715, 1632 (C=O stretching); 736, 693, 646, 589 (C–Cl stretching). 75 …”

Section: Methodsmentioning

confidence: 99%

Facile and Bioinspired Approach from Gallic Acid for the Synthesis of Biobased Flame Retardant Coatings of Basalt Fibers

Pantaleoni,

Sarasini,

Russo

et al. 2024

ACS Omega

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A sustainable, bioinspired approach to functionalize basalt fibers with an innovative gallic acid (GA)-iron phenyl phosphonate complex (BF-GA-FeP), for the purpose of improving the flame retardancy in composite materials, is developed. BFs were at first pretreated with O 3 , obtaining surface free hydroxyl groups that allowed the subsequent covalent immobilization of biosourced GA units on the fiber through ester linkages. Phenolic −OH groups of the GA units were then exploited for the complexation of iron phenyl phosphonate, resulting in the targetcomplex-coated BF fiber (BF-GA-FeP). Microwave plasma atomic emission spectroscopy and scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy analyses of BF-GA-FeP highlighted an increase in iron content, modification of fiber morphology, and occurrence of phosphorus, respectively. BFs, modified with a low amount of the developed complex, were used to reinforce a poly(lactic acid) (PLA) matrix in the production of a biocomposite (PLA/BF-FeP). PLA/BF-FeP showed a higher thermal stability than neat PLA and PLA reinforced with untreated BFs (PLA/BF), as confirmed by thermogravimetric analysis. The cone calorimeter test highlighted several advantages for PLA/BF-FeP, including a prolonged time to ignition, a reduced time to flame out, an 8% decrease in the peak heat release rate, and a 15% reduced fire propagating index compared to PLA/BF.

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Synthesis, Urease Inhibition, Antimicrobial and Antioxidant Studies of 3,4,5-Trihydroxy Benzoic Acid Derivatives

Cited by 2 publications

References 11 publications

A study on phytochemical composition, antioxidant, and anti-cancer activities of Gingko biloba L.

A study on phytochemical composition, antioxidant, and anti-cancer activities of Gingko biloba L.

Facile and Bioinspired Approach from Gallic Acid for the Synthesis of Biobased Flame Retardant Coatings of Basalt Fibers

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