Synthesized evidence for childhood acute lymphoblastic leukemia

Onyije, Felix M.; Olsson, Ann; Bouaoun, Liacine; Schüz, Joachim

doi:10.3389/fped.2023.1209330

Cited by 1 publication

(1 citation statement)

References 13 publications

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“…However, this needs to be taken with caution as few articles regarding EMFs were included in this study [ 188 ]. A more recent review of the same author confirmed the convincing evidence of the pesticide exposure association with acute lymphoblastic leukemia risk, and found little evidence for radon association with this cancer [ 204 ]. In addition, a 2021 scoping review of environmental risk factors and all types of childhood cancer mostly found articles regarding air pollution, chemical exposures, radiation, and residential locations.…”

Section: Discussionmentioning

confidence: 99%

Environmental Pollution and Risk of Childhood Cancer: A Scoping Review of Evidence from the Last Decade

Navarrete-Meneses,

Salas-Labadía,

Gómez-Chávez

et al. 2024

IJMS

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The long-term effects of environmental pollution have been of concern as several pollutants are carcinogenic, potentially inducing a variety of cancers, including childhood cancer, which is a leading cause of death around the world and, thus, is a public health issue. The present scoping review aimed to update and summarize the available literature to detect specific environmental pollutants and their association with certain types of childhood cancer. Studies published from 2013 to 2023 regarding environmental pollution and childhood cancer were retrieved from the PubMed database. A total of 174 studies were eligible for this review and were analyzed. Our search strategy brought up most of the articles that evaluated air pollution (29%) and pesticides (28%). Indoor exposure to chemicals (11%), alcohol and tobacco use during pregnancy (16%), electromagnetic fields (12%), and radon (4%) were the subjects of less research. We found a particularly high percentage of positive associations between prenatal and postnatal exposure to indoor (84%) and outdoor (79%) air pollution, as well as to pesticides (82%), and childhood cancer. Positive associations were found between leukemia and pesticides and air pollution (33% and 27%); CNS tumors and neuroblastoma and pesticides (53% and 43%); and Wilms tumor and other rare cancers were found in association with air pollution (50%). Indoor air pollution was mostly reported in studies assessing several types of cancer (26%). Further studies are needed to investigate the mechanisms underlying the potential associations between indoor/outdoor air pollution and pesticide exposure with childhood cancer risk as more preventable measures could be taken.

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Section: Discussionmentioning

confidence: 99%