Synthetic applications of 2-aryl-4-piperidones. V1.

Rubiralta, Mario; Marco, M.‐Pilar; Bolós, J.; Trape, J.

doi:10.1016/s0040-4020(01)80990-x

Cited by 7 publications

(4 citation statements)

References 44 publications

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“…Fruticosoline, a new minor alkaloid of Aristotelia fruticosa Hook. f., has the structure (151), since it can be oxidized by Jones's reagent to the corresponding ketone, which was identified as fruticosonine ; the configuration of the hydroxygroup in (151) is at present unknown. 81 Two new alkaloids from the aerial parts of A .…”

Section: Alkaloids Containing An Unrearranged Monoterpenoid Unitmentioning

confidence: 99%

Recent progress in the chemistry of indole alkaloids and mould metabolites

Saxton¹

1992

Nat. Prod. Rep.

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Volume 38 in the Manske-Brossi series of alkaloid monographs contains a review of recent work on the ergot alkaloids;' and Volume 39 includes a survey of the betalains2" and a summary of recent syntheses and antitumour activity of ellipticine and related alkaloids.2* In a second review, the same author has discussed synthetic approaches to the ellipticine group via metalation and cycloaddition ~h e m i s t r y . ~ Volume 5 in the series ' Studies in Natural Product Chemistry' contains chapters on applications of NMR spectroscopy to structure el~cidation,~" and the mass spectrometry of the

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Section: Alkaloids Containing An Unrearranged Monoterpenoid Unitmentioning

confidence: 99%

Recent progress in the chemistry of indole alkaloids and mould metabolites

Saxton¹

1992

Nat. Prod. Rep.

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“…Moreover, this structural moiety has also been explored as a useful synthon for the syntheses of structurally diverse complex heterocycles such as benzo-[a]-quinazolidine-2-ones, 8 hexahydropyrido-[3,4-c]-[1,5]-benzothiazepines, 9 5-(diethoxyphosphoryl)-1-aryl-2-alkyl/aryl-2,3dihydro-4-pyridones, 10 3-aminopiperidines, 11 methyl-indolo-[2,3-a]-quinazolidin-2-acetate; 12 for the synthesis of various alkaloids such as guettardine, 15-epiguettardine, 13 E-azaburnamine, 14 makaluvamine A&C, 15 veiutamine; 16 and for the synthesis of the fundamental tetracyclic skeleton of ervitsine and 20-de-ethylidine-6,16-dihydro analogues. 17 In view of their importance and wide applications, their syntheses have gained considerable attention, and therefore have become a focus of synthetic organic chemistry.…”

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confidence: 99%

An efficient and novel approach for the synthesis of substituted N-aryl lactams

Chaturvedi

Mishra

et al. 2012

Org. Biomol. Chem.

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A quick, efficient, one-pot method for the synthesis of substituted N-aryl lactams through the reaction of various kinds of corresponding substituted arenes with a variety of ω-azido alkanoic acid chlorides using a Lewis acid (i.e. EtAlCl(2)) at room temperature, through the in situ involvement of a Friedel-Crafts reaction followed by intramolecular Schimdt rearrangement was developed, and afforded good to excellent yields.

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“…Moreover, this structural moiety has also been explored as a useful synthon for the syntheses of structurally diverse complex heterocycles such as benzo[a]quinazolidine-2-ones, 8 hexahydropyrido[3,4-c][1,5]benzothiazepines, 9 5-(diethoxyphosphoryl)-1-aryl-2-alkyl/aryl-2,3-dihydro-4-pyridones, 10 3-aminopiperidines, 11 methyl indolo[2,3-a]quinazolidin-2-acetate, 12 and synthesis of various alkaloids such as guettardine, 15-epiguettardine, 13 (E)-azaburnamine, 14 makaluvamine A and C, 15 veiutamine, 16 and synthesis of the fundamental tetracyclic skeleton of ervitsine and 20-de-ethylidine-6,16-dihydro analogues. 17 In view of their importance and wide applications, their synthesis has gained considerable attention, and therefore, become a focus of synthetic organic chemistry.…”

mentioning

confidence: 99%