Synthetic Applications of Dienes and Polyenes, Excluding Cycloadditions

Abstract

Introduction Addition Reactions Oxidation Reactions Coupling Reactions Dimerization Reactions Preparation of Metal‐Polyene Complexes Rearrangements

Stereoconvergent Synthesis of Monofluoroalkenes via Photoinduced Dual Decarboxylative Cross-Coupling of α-Fluoroacrylic Acids with Redox-Active Esters

“…1,4-Alkyl-substituted conjugated dienes are found in a diversity of natural products and pharmaceutically active compounds. They are also key synthetic building blocks used in organic synthesis and materials science . Thus, the construction of these structural motifs is a particularly well-developed subset of modern organic synthesis.…”

Regioselective 1,4-/1,3-Difunctionalization of 1,3-Enynes with Selenosulfonates in Water

“…As a specialized structure in which olefins and alkynes are directly linked, 1,3-enynes have high reactivity and a large number of reactive sites. 1,3-Enynes have been developed as versatile structural units to obtain a variety of highly useful molecular architectures, including alkyne-propyl compounds, biphenyls, and dienes . Based on the specificity of the 1,3-enyne-containing skeleton and our group’s research on sulfur and selenium compounds, we envisioned whether we could cleverly design compounds containing the 1,3-enyne skeleton and sulfur and selenium-containing elements to synthesize the connecting skeleton.…”

Regiodivergent sulfonylarylation of 1,3-enynes via nickel/photoredox dual catalysis

“…Owing to their ambident reactivity and ready availability, 1,3enynes have been exploited as versatile building blocks to access various highly useful molecular architectures, 1 including: propargylic compounds, 2 allenes 3 and dienes. 4 Transition-metal catalyzed difunctionalization of unactivated 1,3-enynes represents one of the most powerful approaches. 5,6 In this context, radical 1,4-difunctionalization of 1,3-enynes has drawn much attention recently, 7 and reports from the groups of Liu, 7a Bao, 7b-7d Liu, 7e and Wang, 7h among others, demonstrated practicality and great potential of such synthetic strategies.…”