2023
DOI: 10.1101/2023.09.22.559060
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Synthetic control of actin polymerization and symmetry breaking in active protocells

Shiva Razavi,
Felix Wong,
Bedri Abubaker-Sharif
et al.

Abstract: Non-linear biomolecular interactions on the membranes drive membrane remodeling that underlies fundamental biological processes including chemotaxis, cytokinesis, and endocytosis. The multitude of biomolecules, the redundancy in their interactions, and the importance of spatiotemporal context in membrane organization hampers understanding the physical principles governing membrane mechanics. A minimal, in vitro system that models the functional interactions between molecular signaling and membrane remodeling, … Show more

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