2011
DOI: 10.1118/1.3633895
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Synthetic CT: Simulating low dose single and dual energy protocols from a dual energy scan

Abstract: This work describes and validates the synthetic CT theory and algorithm by comparing its results to actual scans. Synthetic CT is a powerful new tool that allows users to realistically see how protocol selection affects CT images and enables radiologists to retrospectively identify the lowest dose protocol achievable that provides diagnostic quality images on real patients.

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Cited by 17 publications
(20 citation statements)
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“…For the same reason, CT images of the CIRS Model 059 breast phantom structure reconstructed from direct measurements using energy of 80 keV or 140 keV, did not allow to recognize heterogeneous areas. However, inclusions in the phantom gel could be visualised on secondary reconstruction images obtained in dual-energy CT examination at the virtual energy level of 40 keV (Wang, Pelc, 2011). The visualised inclusions have sharply delineated edges but are hardly distinguishable from the phantom gel background (the contrast values between structures and the background contain in the maximum range 0÷6 dB and the average value is about 3 dB, see Table 1) even with increased image contrast (Fig.…”
Section: Computed Tomographymentioning
confidence: 99%
See 1 more Smart Citation
“…For the same reason, CT images of the CIRS Model 059 breast phantom structure reconstructed from direct measurements using energy of 80 keV or 140 keV, did not allow to recognize heterogeneous areas. However, inclusions in the phantom gel could be visualised on secondary reconstruction images obtained in dual-energy CT examination at the virtual energy level of 40 keV (Wang, Pelc, 2011). The visualised inclusions have sharply delineated edges but are hardly distinguishable from the phantom gel background (the contrast values between structures and the background contain in the maximum range 0÷6 dB and the average value is about 3 dB, see Table 1) even with increased image contrast (Fig.…”
Section: Computed Tomographymentioning
confidence: 99%
“…5). The CT examination was performed using a dual-energy protocol: 80 keV and 140 keV (Wang, Pelc, 2011). Next, secondary reconstructions of images for energy of 40 keV were obtained using dedicated software (GSI Viewer, GE Healthcare).…”
Section: Methodsmentioning
confidence: 99%
“…Then, the readout noise becomes significant and the measured signal is best described by compound Poisson statistics [12] [13] [14]. Still, many low--dose CT--simulators have merely added Gaussian noise to the raw projection data [8] [15] [16] [7]. Zabic et al [17] extended the noise model to correctly reflect the noise (co)variances under photon--starvation conditions and appropriately simulate detector noise artifacts.…”
Section: Related Workmentioning
confidence: 99%
“…For the same reason the CT images of the CIRS Model 059 breast phantom structure reconstructed from direct measurements using energy of 80 keV or 140 keV did not allow recognition of heterogeneous areas. Inclusions in the phantom gel were only visualised on secondary reconstructions of images of dual-energy CT examination (Wang, Pelc, 2011) (energy of 40 keV). Using this method it is possible to simulate an enhanced mammographic image without the need to mechanically compress the phantom as this would cause damage.…”
Section: Measurementsmentioning
confidence: 99%