Synthetic open cell foams versus a healthy human vertebra: Anisotropy, fluid flow and μ-CT structural studies

González, Sergio Gómez; Jiménez, José Fernando Valera; Bastida, Gerard Cabestany; Vlad, Maria; López, José López; Aguado, Enrique Fernández

doi:10.1016/j.msec.2019.110404

Cited by 6 publications

(4 citation statements)

References 45 publications

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“…The second approach of IBSim in biomimicry makes use of the imagining data with high resolution simulations to virtually qualify the constructed biomaterial architectures [ 330 – 332 ]. The alternative architectures, which are analogues to the real biomaterials in terms of statistical data, can be manufactured as a replacement to the original material.…”

Section: Review Of Hvm Applications Of Ibsimmentioning

confidence: 99%

“…To demonstrate the use of IBSim with foam materials, a commercial synthetic foam (open-cell) was considered as a replacement to human cadaveric bone Synthetic to simulate various in-vitro cases for bone infiltration (see Fig. 37 ) [ 332 ]. The procedure to be followed is listed as i) μCT scanning of the sample materials and saving the images in DICOM file format, ii) importing the images in Simpleware Software (Synopsys Inc.) and applying a list of postprocessing operations—in particular, noise reduction, smoothing, automated segmentation, iii) construction of foam volume, iv) Boolean operation to obtain complex flow volume, v) meshing the flow volume with tetrahedral elements, vi) applying prescribed boundary conditions, inlet flow velocity, outlet pressure and slip/nonslip boundaries.…”

Section: Review Of Hvm Applications Of Ibsimmentioning

confidence: 99%

“…

Fig. 37 Flow behaviour over porous scaffold geometry directly obtained from CT images can be achieved with a list of steps: a stack of μCT images, b binarisation and smoothing of the selected volume of interest, c 3D reconstruction and segmentation of the structure, d Boolean operation over the structural geometry to produce the flow domain (i.e., CFD domain), e meshing process of IBSim CFD model, f assigning various boundary conditions (inlet velocity, outlet pressure and wall boundary conditions) [ 332 ] …”

Section: Review Of Hvm Applications Of Ibsimmentioning

confidence: 99%

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A Review of Image-Based Simulation Applications in High-Value Manufacturing

Evans

Sozumert

Keenan

et al. 2023

Arch Computat Methods Eng

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Image-Based Simulation (IBSim) is the process by which a digital representation of a real geometry is generated from image data for the purpose of performing a simulation with greater accuracy than with idealised Computer Aided Design (CAD) based simulations. Whilst IBSim originates in the biomedical field, the wider adoption of imaging for non-destructive testing and evaluation (NDT/NDE) within the High-Value Manufacturing (HVM) sector has allowed wider use of IBSim in recent years. IBSim is invaluable in scenarios where there exists a non-negligible variation between the ‘as designed’ and ‘as manufactured’ state of parts. It has also been used for characterisation of geometries too complex to accurately draw with CAD. IBSim simulations are unique to the geometry being imaged, therefore it is possible to perform part-specific virtual testing within batches of manufactured parts. This novel review presents the applications of IBSim within HVM, whereby HVM is the value provided by a manufactured part (or conversely the potential cost should the part fail) rather than the actual cost of manufacturing the part itself. Examples include fibre and aggregate composite materials, additive manufacturing, foams, and interface bonding such as welding. This review is divided into the following sections: Material Characterisation; Characterisation of Manufacturing Techniques; Impact of Deviations from Idealised Design Geometry on Product Design and Performance; Customisation and Personalisation of Products; IBSim in Biomimicry. Finally, conclusions are drawn, and observations made on future trends based on the current state of the literature.

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Section: Review Of Hvm Applications Of Ibsimmentioning

confidence: 99%

Section: Review Of Hvm Applications Of Ibsimmentioning

confidence: 99%

“…

Section: Review Of Hvm Applications Of Ibsimmentioning

confidence: 99%

See 1 more Smart Citation

A Review of Image-Based Simulation Applications in High-Value Manufacturing

Evans

Sozumert

Keenan

et al. 2023

Arch Computat Methods Eng

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“…By creating a functional spine out of synthetic materials, this restriction can be removed. Artificial materials are now frequently utilised as an alternative in biomechanical testing, particularly when examining trabecular bone [ 4 , 5 ]. This initiates the process of creating a functional synthetic spine model for biomechanical investigation [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Finite Element Modelling of a Synthetic Paediatric Spine for Biomechanical Investigation

et al. 2023

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Studies on paediatric spines commonly use human adult or immature porcine spines as specimens, because it is difficult to obtain actual paediatric specimens. There are quite obvious differences, such as geometry, size, bone morphology, and orientation of facet joint for these specimens, compared to paediatric spine. Hence, development of synthetic models that can behave similarly to actual paediatric spines, particularly in term of range of motion (ROM), could provide a significant contribution for paediatric spine research. This study aims to develop a synthetic paediatric spine using finite element modelling and evaluate the reliability of the model by comparing it with the experimental data under certain load conditions. The ROM of the paediatric spine was measured using a validated FE model at ±0.5 Nm moment in order to determine the moment required by the synthetic spine to achieve the same ROM. The results showed that the synthetic spine required two moments, ±2 Nm for lateral-bending and axial rotation, and ±3 Nm for flexion-extension, to obtain the paediatric ROM. The synthetic spine was shown to be stiffer in flexion-extension but more flexible in lateral bending than the paediatric FE model, possibly as a result of the intervertebral disc’s simplified shape and the disc’s weak bonding with the vertebrae. Nevertheless, the synthetic paediatric spine has promising potential in the future as an alternative paediatric spine model for biomechanical investigation of paediatric cases.

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Comprehensive Evaluation of Biomechanical and Biological Properties of the Porous Irregular Scaffolds Based on Voronoi-tessellation

Wang,

Ma,

et al. 2024

J Bionic Eng

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Synthetic open cell foams versus a healthy human vertebra: Anisotropy, fluid flow and μ-CT structural studies

Cited by 6 publications

References 45 publications

A Review of Image-Based Simulation Applications in High-Value Manufacturing

A Review of Image-Based Simulation Applications in High-Value Manufacturing

Finite Element Modelling of a Synthetic Paediatric Spine for Biomechanical Investigation

Comprehensive Evaluation of Biomechanical and Biological Properties of the Porous Irregular Scaffolds Based on Voronoi-tessellation

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